Entry Detail


General Information

Database ID:TRD00172
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-1:33-Gly-GCC-2-M3
tsRNA Type:5'-tiRNA
Amino acid and Anticodon:GlyGCC
Sequence:GCATTGGTGGTTCAGTGGTAGAATTCTCGCCTG
Related Target:N/A
Predicted Target:FCGR2A//DPF1//ABLIM2//LPAR1//COL6A5//ERAS//SLC26A6//ST3GAL2//ZNF26//CACNA1E
External Links:
MINTbase ID:tRF-33-PNR8YP9LON4VDP
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822597        End Site(bp): 70822629

[2] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812152        End Site(bp): 70812184

[3] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493675        End Site(bp): 161493707

[4] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823410        End Site(bp): 70823442

[5] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812980        End Site(bp): 70813012

[6] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029064        End Site(bp): 8029096

[7] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257697        End Site(bp): 157257729

[8] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870724        End Site(bp): 27870756



tsRNA Association Statistics

Total Associated Disease Number:3
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D005909DOID:3068
Disease Name:Glioblastomaglioblastoma
Category:MeSHDisease Ontology
Type:Neoplasmsdisease of anatomical entity//disease of cellular proliferation
Define:A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes.
Alias:Astrocytoma, Grade IV//Giant Cell Glioblastoma//Glioblastoma Multiformeadult glioblastoma multiforme//GBM//glioblastoma multiforme//grade IV adult Astrocytic tumor//primary glioblastoma multiforme//spongioblastoma multiforme



Disease Association Statistics

Total Associated tsRNA Number:32
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:36526122
Disease Name:Glioblastoma
Tissue:Glioblastoma
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:A total of 9 tsRNAs were selected as candidate tsRNAs according to the tsRNA expression level, among which 6 tsRNAs were highly expressed in GBMs and 5 tsRNAs were low expressed in GBMs.
Comparision:Subtype1 VS Subtype2
Mechanism:N/A