The tsRNA and Disease Database (version 1.0)
| Disease | DO_ID | DO_Name | DO_Type | DO_Define |
|---|---|---|---|---|
| Alzheimer Disease | DOID:10652 | Alzheimer's disease | disease of anatomical entity | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| Amyotrophic Lateral Sclerosis | DOID:332 | amyotrophic lateral sclerosis | disease of anatomical entity | A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. |
| Cartilage Diseases | DOID:1222 | cartilage disease | disease of anatomical entity | A connective tissue disease that is located_in cartilage. |
| Dermatitis, Atopic | DOID:3310 | atopic dermatitis | disease of anatomical entity//integumentary system disease | An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking. |
| Diabetic Foot | N/A | N/A | N/A | N/A |
| Fibrous Dysplasia of Bone | DOID:0080031 | fibrous dysplasia | disease of anatomical entity | A bone remodeling disease that results_in the destruction of normal bone and replacing it with fibrous bone tissue. |
| Graves Ophthalmopathy | DOID:0081120 | Graves ophthalmopathy | disease of anatomical entity | An autoimmune disease of eyes, ear, nose and throat that is characterized by upper eyelid retraction, lid lag, swelling, redness, conjunctivitis, and bulging eyes. |
| Keloid | N/A | N/A | N/A | N/A |
| Lupus Erythematosus, Systemic | DOID:9074 | systemic lupus erythematosus | disease of anatomical entity | A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart. |
| Mitochondrial Diseases | N/A | N/A | N/A | N/A |
| Multiple Sclerosis | DOID:2377 | multiple sclerosis | disease of anatomical entity//nervous system disease | A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. |
| Multiple Sclerosis, Relapsing-Remitting | DOID:2378 | relapsing-remitting multiple sclerosis | disease of anatomical entity//nervous system disease | A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles. |
| Neurodegenerative Diseases | DOID:1289 | neurodegenerative disease | disease of anatomical entity | A central nervous system disease that results in the progressive deterioration of function or structure of neurons. |
| Osteoarthritis | DOID:8398 | osteoarthritis | disease of anatomical entity | An arthritis that has_material_basis_in worn out cartilage located_in joint. |
| Osteoporosis | DOID:11476 | osteoporosis | disease of anatomical entity | A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength. |
| Parkinson Disease | DOID:14330 | Parkinson's disease | disease of anatomical entity | A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. |
| Psoriasis | DOID:8893 | psoriasis | disease of anatomical entity | A skin disease that is characterized by patches of thick red skin and silvery scales. |
| Skin Diseases | DOID:10123 | pigmentation disease | disease of anatomical entity | A skin disease that is characterized by discoloration of the skin. |
| Sleep Apnea, Obstructive | DOID:0050848 | obstructive sleep apnea | disease of mental health | A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep. |
| Spinal Cord Injuries | N/A | N/A | N/A | N/A |
| Traumatic Brain | N/A | N/A | N/A | N/A |