The tsRNA and Disease Database (version 1.0)
| Disease | DO_ID | DO_Name | DO_Type | DO_Define |
|---|---|---|---|---|
| Alzheimer Disease | DOID:10652 | Alzheimer's disease | disease of anatomical entity | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| Aortic dissection | DOID:0080685 | aortic dissection | disease of anatomical entity | An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall. |
| Aortic Dissection | DOID:0080685 | aortic dissection | disease of anatomical entity | An aortic disease that is characterized by tearing of the intimal layer of the aorta resulting in separation of the layers of the aortic wall. |
| Atherosclerosis | DOID:1936 | atherosclerosis | disease of anatomical entity | N/A |
| Atrial Fibrillation | DOID:0060224 | atrial fibrillation | disease of anatomical entity | A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has symptoms palpitations, weakness, fatigue, lightheadedness, dizziness, confusion, shortness of breath and chest pain. |
| Cardiomegaly | N/A | N/A | N/A | N/A |
| Cardiomyopathy, Dilated | DOID:12930 | dilated cardiomyopathy | disease of anatomical entity | An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently. |
| Cardiomyopathy, Hypertrophic | DOID:11984 | hypertrophic cardiomyopathy | disease of anatomical entity | An intrinsic cardiomyopathy that is characterized by abnormal thickening (hypertrophy) of the heart without any obvious cause. |
| Carotid Artery Injuries | DOID:3407 | carotid artery disease | disease of anatomical entity | N/A |
| Diabetic Angiopathies | DOID:11713 | diabetic angiopathy | disease of anatomical entity | A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes. |
| Diabetic Retinopathy | DOID:13207 | proliferative diabetic retinopathy | disease of anatomical entity//nervous system disease | N/A |
| Heart Defects, Congenital | DOID:1682 | congenital heart disease | physical disorder//disease of anatomical entity | N/A |
| Heart Failure | N/A | N/A | N/A | N/A |
| Hypertension | DOID:10763 | hypertension | disease of anatomical entity | An artery disease characterized by chronic elevated blood pressure in the arteries. |
| Intracranial Aneurysm | DOID:10941 | intracranial aneurysm | disease of anatomical entity//nervous system disease | N/A |
| Moyamoya disease | DOID:13099 | Moyamoya disease | disease of anatomical entity//nervous system disease | A cerebral arterial disease characterized by constriction of certain arteries at the base of the brain. Blood flow is blocked by the constriction and also by blood clots. |
| Moyamoya Disease | DOID:13099 | Moyamoya disease | disease of anatomical entity//nervous system disease | A cerebral arterial disease characterized by constriction of certain arteries at the base of the brain. Blood flow is blocked by the constriction and also by blood clots. |
| Myocardial Infarction | DOID:5844 | myocardial infarction | disease of anatomical entity | A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia. |
| Myocardial Ischemia | N/A | N/A | N/A | N/A |
| Myocarditis | DOID:820 | myocarditis | disease of anatomical entity | An extrinsic cardiomyopathy that is characterized as an inflammation of the heart muscle. |
| Reperfusion Injury | N/A | N/A | N/A | N/A |
| Rheumatic Heart Disease | DOID:0050827 | rheumatic heart disease | disease of anatomical entity | A heart valve disease that is characterized by repeated inflammation with fibrinous repair caused by an autoimmune reaction to Group A beta-hemolytic streptococci (GAS) that results in valvular damage. The cardinal anatomic changes of the valve include leaflet thickening, commissural fusion, and shortening and thickening of the tendinous cords. |
| Stroke | N/A | N/A | N/A | N/A |
| Varicose Veins | DOID:799 | varicose veins | disease of anatomical entity | A vein disease that is characterized by swollen, twisted veins visible just under the surface of the skin. |