The tsRNA and Disease Database (version 1.0)
| Disease | DO_ID | DO_Name | DO_Type | DO_Define |
|---|---|---|---|---|
| Alzheimer Disease | DOID:10652 | Alzheimer's disease | disease of anatomical entity | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| Depressive Disorder, Major | DOID:1470 | major depressive disorder | disease of mental health | A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality. |
| Graves Ophthalmopathy | DOID:0081120 | Graves ophthalmopathy | disease of anatomical entity | An autoimmune disease of eyes, ear, nose and throat that is characterized by upper eyelid retraction, lid lag, swelling, redness, conjunctivitis, and bulging eyes. |
| Macular Degeneration | DOID:10871 | age related macular degeneration | disease of anatomical entity//genetic disease | A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision. |
| Multiple Sclerosis | DOID:2377 | multiple sclerosis | disease of anatomical entity//nervous system disease | A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. |
| Multiple Sclerosis, Relapsing-Remitting | DOID:2378 | relapsing-remitting multiple sclerosis | disease of anatomical entity//nervous system disease | A multiple sclerosis that is characterized by relapse (attacks of symptom flare-ups) followed by remission (periods of recovery). Symptoms may vary from mild to severe, and relapses and remissions may last for days or months. More than 80 percent of people who have MS begin with relapsing-remitting cycles. |
| Neurodegenerative Diseases | DOID:1289 | neurodegenerative disease | disease of anatomical entity | A central nervous system disease that results in the progressive deterioration of function or structure of neurons. |
| Parkinson Disease | DOID:14330 | Parkinson's disease | disease of anatomical entity | A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions. |
| Respiratory Syncytial Virus Infection | N/A | N/A | N/A | N/A |