The tsRNA and Disease Database (version 1.0)
| Disease | DO_ID | DO_Name | DO_Type | DO_Define |
|---|---|---|---|---|
| Alzheimer Disease | DOID:10652 | Alzheimer's disease | disease of anatomical entity | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| Amyotrophic Lateral Sclerosis | DOID:332 | amyotrophic lateral sclerosis | disease of anatomical entity | A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing. |
| Brain Injuries, Traumatic | DOID:0081292 | traumatic brain injury | disease of anatomical entity | A brain disease that is characterized by brain dysfunction caused by an outside force, usually a violent blow to the head. |
| Carotid Artery Injuries | DOID:3407 | carotid artery disease | disease of anatomical entity | N/A |
| Epilepsy | DOID:1826 | epilepsy | disease of anatomical entity | A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions. |
| Multiple Sclerosis | DOID:2377 | multiple sclerosis | disease of anatomical entity//nervous system disease | A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. |
| Neurodegenerative Diseases | DOID:1289 | neurodegenerative disease | disease of anatomical entity | A central nervous system disease that results in the progressive deterioration of function or structure of neurons. |
| Spinal Cord Injuries | N/A | N/A | N/A | N/A |