The tsRNA and Disease Database (version 1.0)
| Disease | DO_ID | DO_Name | DO_Type | DO_Define |
|---|---|---|---|---|
| Alzheimer Disease | DOID:10652 | Alzheimer's disease | disease of anatomical entity | A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. |
| Depressive Disorder, Major | DOID:1470 | major depressive disorder | disease of mental health | A depressive disorder that is characterized by at least two weeks of loss of interest or pleasure in normally enjoyable activities or depressed mood along with additional cognitive or somatic impairments such as appetite or weight changes, sleep difficulties, psychomotor agitation or retardation, fatigue or loss of energy, diminished ability to think or concentrate, feelings of worthlessness or excessive guilt, and suicidality. |
| Diabetes Mellitus | DOID:9351 | diabetes mellitus | disease of metabolism//genetic disease | A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. |
| Diabetes Mellitus, Type 2 | DOID:9352 | type 2 diabetes mellitus | disease of metabolism//genetic disease | A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. |
| Diabetic Angiopathies | DOID:11713 | diabetic angiopathy | disease of anatomical entity | A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes. |
| Diabetic Foot | N/A | N/A | N/A | N/A |
| Diabetic Retinopathy | DOID:13207 | proliferative diabetic retinopathy | disease of anatomical entity//nervous system disease | N/A |
| Diffuse Intrinsic Pontine Glioma | DOID:0080880 | diffuse glioma, H3 G34 mutant | disease of cellular proliferation | A histone mutated tumor that has_material_basis_in mutations in codon 34 of the H3 histone family 3A protein. |
| Glioblastoma | DOID:3068 | glioblastoma | disease of anatomical entity//disease of cellular proliferation | A malignant astrocytoma characterized by the presence of small areas of necrotizing tissue that is surrounded by anaplastic cells as well as the presence of hyperplastic blood vessels, and that has_material_basis_in abnormally proliferating cells derives_from multiple cell types including astrocytes and oligondroctyes. |
| Glioma | DOID:0060108 | brain glioma | disease of cellular proliferation//disease of anatomical entity | A brain cancer that has_material_basis_in glial cells. |
| Graves Ophthalmopathy | DOID:0081120 | Graves ophthalmopathy | disease of anatomical entity | An autoimmune disease of eyes, ear, nose and throat that is characterized by upper eyelid retraction, lid lag, swelling, redness, conjunctivitis, and bulging eyes. |
| Macular Degeneration | DOID:10871 | age related macular degeneration | disease of anatomical entity//genetic disease | A degeneration of macula and posterior pole that is characterized by a loss of vision in the center of the visual field (the macula) resulting from damage to the retina and resulting in blurring of the sharp central vision. |
| Mitochondrial Diseases | N/A | N/A | N/A | N/A |
| Stroke | N/A | N/A | N/A | N/A |