Entry Detail


General Information

Database ID:TRD05564
Confidence:Very High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tsRNA-Asp-5-0002
tsRNA Type:N/A
Amino acid and Anticodon:N/A
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006528DOID:684
Disease Name:Carcinoma, Hepatocellularhepatocellular carcinoma
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver.
Alias:Hepatocellular Carcinoma//Hepatoma//Liver Cancer, Adult//Liver Cell Carcinoma//Liver Cell Carcinoma, AdultHepatoma



Disease Association Statistics

Total Associated tsRNA Number:61
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR//Western blot//Transfection//Cell proliferation assay//Transwell assay
Weak Evidence:Data Mining



Reference

[1] PubMed ID:40164240
Disease Name:Carcinoma, Hepatocellular
Tissue:Liver
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//Western blot//Transfection//Cell proliferation assay//Transwell assay//Data Mining
Description:tsRNA-Asp-5-0002 is down-regulated in HCC.
Comparision:Cancer VS Normal
Mechanism:qRT-PCR detection tsRNA-Asp-5-0002 had high sensitivity and specificity.Low-expressed tsRNA-Asp-5-0002 was related to TNM stage, differentiation, and LNM, and the ROC curve indicated that tsRNA-Asp-5-0002 had a better diagnostic performance for HCC.tsRNA-Asp-5-0002 inhibits the proliferation and migration of HCC through the PLCB1/Wnt axis.