Entry Detail


General Information

Database ID:TRD05379
Confidence:Very High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-29-79MP9P9NH525
tsRNA Type:N/A
Amino acid and Anticodon:N/A
Sequence:GTTTCCGTAGTGTAGTGGTTATCACGTTC
Related Target:N/A
Predicted Target:ZBED2//CTNND2//SREBF2//TNFRSF10B//NEFL//LDLRAD1//FAM171A1//MYH6//ADAR//HK2
External Links:
MINTbase ID:tRF-29-79MP9P9NH525
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Val-AAC-4-1
Anticodon:ValAAC
tRNA_number:trna136
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27648929        End Site(bp): 27648957

[2] gtRNAdb_ID:tRNA-Val-AAC-3-1
Anticodon:ValAAC
tRNA_number:trna139
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27618751        End Site(bp): 27618779

[3] gtRNAdb_ID:tRNA-Val-AAC-1-1
Anticodon:ValAAC
tRNA_number:trna2
Chromosome:3
Strand:+
Coordinate:Start Site(bp): 169490018        End Site(bp): 169490046

[4] gtRNAdb_ID:tRNA-Val-AAC-1-4
Anticodon:ValAAC
tRNA_number:trna12
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180645314        End Site(bp): 180645342

[5] gtRNAdb_ID:tRNA-Val-AAC-1-2
Anticodon:ValAAC
tRNA_number:trna4
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180591154        End Site(bp): 180591182

[6] gtRNAdb_ID:tRNA-Val-AAC-1-3
Anticodon:ValAAC
tRNA_number:trna5
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180596610        End Site(bp): 180596638

[7] gtRNAdb_ID:tRNA-Val-AAC-1-5
Anticodon:ValAAC
tRNA_number:trna132
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27721223        End Site(bp): 27721251

[8] gtRNAdb_ID:tRNA-Val-CAC-5-1
Anticodon:ValCAC
tRNA_number:trna90
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149684133        End Site(bp): 149684161

[9] gtRNAdb_ID:tRNA-Val-CAC-4-1
Anticodon:ValCAC
tRNA_number:trna98
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149298599        End Site(bp): 149298627

[10] gtRNAdb_ID:tRNA-Val-CAC-1-1
Anticodon:ValCAC
tRNA_number:trna85
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161369534        End Site(bp): 161369562

[11] gtRNAdb_ID:tRNA-Val-CAC-1-5
Anticodon:ValCAC
tRNA_number:trna10
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180649439        End Site(bp): 180649467

[12] gtRNAdb_ID:tRNA-Val-CAC-1-3
Anticodon:ValCAC
tRNA_number:trna18
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180529297        End Site(bp): 180529325

[13] gtRNAdb_ID:tRNA-Val-CAC-1-2
Anticodon:ValCAC
tRNA_number:trna2
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180524070        End Site(bp): 180524098

[14] gtRNAdb_ID:tRNA-Val-CAC-1-4
Anticodon:ValCAC
tRNA_number:trna6
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180600650        End Site(bp): 180600678

[15] gtRNAdb_ID:tRNA-Val-CAC-1-6
Anticodon:ValCAC
tRNA_number:trna9
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26538282        End Site(bp): 26538310



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D013274 DOID:10534
Disease Name:Stomach Neoplasmsstomach cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the STOMACH.A gastrointestinal system cancer that is located_in the stomach.
Alias:Cancer of Stomach//Cancer of the Stomach//Gastric Cancer//Gastric Cancer, Familial Diffuse//Gastric Neoplasms//Neoplasms, Gastric//Neoplasms, Stomach//Stomach Cancergastric cancer//gastric neoplasm



Disease Association Statistics

Total Associated tsRNA Number:79
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:PCR//Western blot//Transfection//Cell proliferation assay//Transwell assay//Cell cycle assay
Weak Evidence:Sequencing



Reference

[1] PubMed ID:40374610
Disease Name:Stomach Neoplasms
Tissue:Stomach
Dysfunction Pattern:Up-Regulation
Validated Method:PCR//Western blot//Transfection//Cell proliferation assay//Transwell assay//Cell cycle assay//Sequencing
Description:tRF-29-79MP9P9NH525 was reduced in both gastric cancer tissues and patients’ plasma
Comparision:Cancer VS Normal
Mechanism:tRF-29 exerted Kinesin family member 14 (KIF14) mRNA destabilization by combining with argonaute 2 (Ago2) and regulated AKT/P27 pathway. In conclusion, tRF-29 inhibited GC progression by combining with Ago2 and regulated AKT/P27 pathway by silencing KIF14 expression.