tsRNADisease

Entry Detail

General Information

Database ID:	TRD05339
Confidence:	High
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

tiRNA-Val-CAC-002

tsRNA Type:

N/A

Amino acid and Anticodon:

N/A

Sequence:

N/A

Related Target:

Predicted Target:

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	25 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D009914	DOID:5773
Disease Name:	Oral Submucous Fibrosis	oral submucous fibrosis
Category:	MeSH	Disease Ontology
Type:	Stomatognathic Diseases	disease of anatomical entity
Define:	Irreversible FIBROSIS of the submucosal tissue of the MOUTH.	A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.
Alias:	N/A	Oral cavity Submucous Fibrosis//Oral submucosal fibrosis//Oral submucosal fibrosis, including of tongue

Disease Association Statistics

Total Associated tsRNA Number:	126 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	PCR//Western blot//Transfection//High-throughput sequencing
Weak Evidence:	High-throughput sequencing

Reference

[1] PubMed ID:	39571899
Disease Name:	Oral Submucous Fibrosis
Tissue:	Oral Cavity
Dysfunction Pattern:	Up-Regulation
Validated Method:	PCR//Western blot//Transfection//High-throughput sequencing//High-throughput sequencing
Description:	The results showed increased expression of tiRNA-Val-CAC-002 in Oral Submucous Fibrosis tissues compared with normal controls (Fig. 1A).
Comparision:	Disease VS Control
Mechanism:	These results suggest that tiRNA-Val-CAC-002 may participate in the regulation of autophagy of FB in OSF through targeted regulation of the ITGB3/PI3K/AKT pathway.