tsRNADisease

Entry Detail

General Information

Database ID:	TRD05268
Confidence:	High
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

5'tiRNA-33-CysGCA-11

tsRNA Type:

N/A

Amino acid and Anticodon:

N/A

Sequence:

N/A

Related Target:

Predicted Target:

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	1 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D002972	DOID:674
Disease Name:	Cleft Palate	cleft palate
Category:	MeSH	Disease Ontology
Type:	Musculoskeletal Diseases//Stomatognathic Diseases//Congenital, Hereditary, and Neonatal Diseases and Abnormalities	physical disorder//syndrome
Define:	Congenital fissure of the soft and/or hard palate, due to faulty fusion.	An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate.
Alias:	Cleft Palate, Isolated	Palatoschisis

Disease Association Statistics

Total Associated tsRNA Number:	2 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	RT-PCR
Weak Evidence:	Microarray

Reference

[1] PubMed ID:	40012056
Disease Name:	Cleft Palate
Tissue:	Oral Cavity
Dysfunction Pattern:	Up-Regulation
Validated Method:	RT-PCR//Microarray
Description:	We found that the expression of 5’tiRNA-35-GlyTCC-3 and 5’tiRNA-33-CysGCA-11 in NSCPO tissues was significantly upregulated
Comparision:	Disease VS Control
Mechanism:	5’TiRNA-35-GlyTCC-3 plays a definite regulatory role in NSCPO disease by targeting CUL1 and BMP6 genes, and 5’tiRNA-33-CysGCA-11 by targeting the SPR gene.