tsRNADisease

Entry Detail

General Information

Database ID:	TRD05088
Confidence:	High
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

tRF-+1:T20-Ser-TGA-1

tsRNA Type:

N/A

Amino acid and Anticodon:

SerTGA

Sequence:

N/A

Related Target:

Predicted Target:

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	1 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D001749	DOID:4006
Disease Name:	Urinary Bladder Neoplasms	bladder urothelial carcinoma
Category:	MeSH	Disease Ontology
Type:	Neoplasms//Urogenital Diseases	disease of cellular proliferation//disease of anatomical entity
Define:	Tumors or cancer of the URINARY BLADDER.	A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.
Alias:	Bladder Cancer//Bladder Neoplasms//Bladder Tumors//Cancer of Bladder//Cancer of the Bladder//Malignant Tumor of Urinary Bladder//Neoplasms, Bladder//Urinary Bladder Cancer	bladder transitional cell carcinoma//transitional cell carcinoma of bladder//urinary bladder urothelial carcinoma//urothelial bladder carcinoma

Disease Association Statistics

Total Associated tsRNA Number:	41 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	PCR
Weak Evidence:	High-throughput sequencing//Data Mining

Reference

[1] PubMed ID:	35456407
Disease Name:	Urinary Bladder Neoplasms
Tissue:	bladder
Dysfunction Pattern:	Down-Regulation
Validated Method:	PCR//High-throughput sequencing//Data Mining
Description:	Compared with paracancerous tissue, in tumor tissue, tiRNA-1:33-Gly-GCC-1 (p-value < 0.01) and tRF-1:32-Gly-GCC-1 (p-value < 0.01) were significantly upregulated, and tRF-+1:T20-Ser-TGA-1 (p-value < 0.01) was significantly downregulated, while tiRNA-1:34-Val-CAC-2 (p-value = 0.0556) was overexpressed without reaching statistical significance.
Comparision:	Tumor VS Paracancer
Mechanism:	N/A