tsRNADisease

Entry Detail

General Information

Database ID:	TRD04924
Confidence:	Very High
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

tRF-1

tsRNA Type:

N/A

Amino acid and Anticodon:

MetCAT

Sequence:

TCGGAGGCTTTGTTTT

Related Target:

Predicted Target:

OBSCN//MAGEA2B//MAGEA2//MAGEA12//CCDC73//PIP5K1C//MAGEA4//HIP1R//ZNF300//FCRL2

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	1 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D029424	DOID:272
Disease Name:	Chronic Obstructive Airway Disease	hepatic vascular disease
Category:	MeSH	Disease Ontology
Type:	Respiratory Tract Diseases//Pathological Conditions, Signs and Symptoms	disease of anatomical entity//gastrointestinal system disease
Define:	A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.	A vascular disease that is located_in the liver.
Alias:	Airflow Obstruction, Chronic//COAD//COPD//Chronic Airflow Obstruction//Chronic Obstructive Airway Disease//Chronic Obstructive Lung Disease//Chronic Obstructive Pulmonary Disease//Chronic Obstructive Pulmonary Diseases	vascular disorder of liver

Disease Association Statistics

Total Associated tsRNA Number:	1 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	RT-PCR
Weak Evidence:	High-throughput sequencing

Reference

[1] PubMed ID:	39587604
Disease Name:	Chronic Obstructive Airway Disease
Tissue:	Lung
Dysfunction Pattern:	N/A
Validated Method:	RT-PCR//High-throughput sequencing
Description:	This study elucidates the differential impacts of intratracheal and intravenous administration of BMSCs and BMSC-EVs on COPD mice at different pathological stages. Intravenous administration of bone marrow mesenchymal stem cells significantly alleviates inflammation and suppresses lung remodeling processes like apoptosis, EMT, and collagen formation.
Comparision:	Disease VS Control
Mechanism:	Intravenous administration of bone marrow mesenchymal stem cells significantly alleviates inflammation and suppresses lung remodeling processes like apoptosis, EMT, and collagen formation.