Entry Detail



General Information

Database ID:TRD04713
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-1-31-His-GTG-1
tsRNA Type:N/A
Amino acid and Anticodon:HisGTG
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:9
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D003924DOID:9352
Disease Name:Diabetes Mellitus, Type 2type 2 diabetes mellitus
Category:MeSHDisease Ontology
Type:Nutritional and Metabolic Diseases//Endocrine System Diseasesdisease of metabolism//genetic disease
Define:A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin.
Alias:Diabetes Mellitus, Adult-Onset//Diabetes Mellitus, Ketosis-Resistant//Diabetes Mellitus, Maturity-Onset//Diabetes Mellitus, Non Insulin Dependent//Diabetes Mellitus, Non-Insulin-Dependent//Diabetes Mellitus, Noninsulin Dependent//Diabetes Mellitus, Noninsulin-Dependent//Diabetes Mellitus, Slow-Onset//Diabetes Mellitus, Stable//Diabetes Mellitus, Type II//MODY//Maturity-Onset Diabetes//Maturity-Onset Diabetes Mellitus//NIDDM//Noninsulin-Dependent Diabetes Mellitus//Type 2 Diabetes//Type 2 Diabetes Mellitusinsulin resistance//NIDDM//non-insulin-dependent diabetes mellitus//type 2 diabetes//type II diabetes mellitus



Disease Association Statistics

Total Associated tsRNA Number:61
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37484941
Disease Name:Diabetes Mellitus, Type 2
Tissue:adipose tissue
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:qRT-PCR evaluation identified a tsRNA with up-regulated expression (tRF-1-28-Glu-TTC-3-M2) and a tsRNA with down-regulated expression (tRF-1-31-His-GTG-1), both of which may be involved in metabolic and energy-related processes.
Comparision:Overweight Group VS Control Group
Mechanism:Both of which may be involved in metabolic and energy-related processes.