Entry Detail



General Information

Database ID:TRD04608
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tiRNA-gly-GCC-1
tsRNA Type:N/A
Amino acid and Anticodon:GlyGCC
Sequence:N/A
Related Target:TLR4
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D001749DOID:4006
Disease Name:Urinary Bladder Neoplasmsbladder urothelial carcinoma
Category:MeSHDisease Ontology
Type:Neoplasms//Urogenital Diseasesdisease of cellular proliferation//disease of anatomical entity
Define:Tumors or cancer of the URINARY BLADDER.A bladder carcinoma that has_material_basis_in transitional cells located_in the lining of the bladder.
Alias:Bladder Cancer//Bladder Neoplasms//Bladder Tumors//Cancer of Bladder//Cancer of the Bladder//Malignant Tumor of Urinary Bladder//Neoplasms, Bladder//Urinary Bladder Cancerbladder transitional cell carcinoma//transitional cell carcinoma of bladder//urinary bladder urothelial carcinoma//urothelial bladder carcinoma



Disease Association Statistics

Total Associated tsRNA Number:41
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:N/A



Reference

[1] PubMed ID:36230476
Disease Name:Urinary Bladder Neoplasms
Tissue:Bladder
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR
Description:As a result, tiRNA-Gly-GCC-1 was significantly upregulated in UBC tissue and might target the predicted target gene toll-like receptor 4 (TLR4) to play a regulatory role in UBC.
Comparision:UBC VS Normal
Mechanism:Besides, tiRNA-Gly-GCC-1 was found to inhibit TLR4 expression by directly targeting its 3′UTR.