Entry Detail


General Information

Database ID:TRD04145
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tsRNA-Gly-GCC-1
tsRNA Type:tRF-5
Amino acid and Anticodon:N/A
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D014376DOID:399
Disease Name:Tuberculosistuberculosis
Category:MeSHDisease Ontology
Type:Infectionsdisease by infectious agent
Define:Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.A primary bacterial infectious disease that is located_in lungs, located_in lymph nodes, located_in pericardium, located_in brain, located_in pleura or located_in gastrointestinal tract, has_material_basis_in Mycobacterium tuberculosis, which is transmitted_by droplets released into the air when an infected person coughs or sneezes.
Alias:Koch's Disease//Kochs Disease//Mycobacterium tuberculosis InfectionN/A



Disease Association Statistics

Total Associated tsRNA Number:5
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:39851057
Disease Name:Tuberculosis
Tissue:serum
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:Levels of tsRNA-Gly-CCC-2, tsRNA-Gly-GCC-1, and tsRNA-Lys-CTT-2-M2 were significantly elevated in the serum of TB patients compared to non-TB individuals, showing a correlation with lung injury severity and acid-fast bacilli grades in TB patients.
Comparision:Tuberculosis and healthy control
Mechanism:After screening the serum tsRNA expression profile of TB patients by high-throughput sequencing, we identified three serum tsRNAs (tsRNA-Gly-CCC-2, tsRNA-Gly-GCC-1 and tsRNA-Lys-CTT-2-M2) for diagnosis of TB. Among three tsRNAs, tsRNA-Gly-CCC-2 were moderately correlated with lung injury severity, while tsRNA-Gly-GCC-1 and tsRNA-Lys-CTT-2-M2 showed a weak correlation.