Entry Detail


General Information

Database ID:TRD04124
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Val-TAC-016
tsRNA Type:tRF-5
Amino acid and Anticodon:ValTAC
Sequence:GGTTCCATAGTGTAGTGGTTATCACGTCTGCT
Related Target:N/A
Predicted Target:CAMK1D//ZNF281//SCAF1//TEDC1//TMBIM6//CYP4F3//SLC35B2//ZNF30//HPS3//RPA1
External Links:
MINTbase ID:tRF-32-R9JP9P9NH5SY3
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Val-TAC-1-1
Anticodon:ValTAC
tRNA_number:trna17
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 59318143        End Site(bp): 59318174

[2] gtRNAdb_ID:tRNA-Val-TAC-1-2
Anticodon:ValTAC
tRNA_number:trna4
Chromosome:X
Strand:-
Coordinate:Start Site(bp): 18693070        End Site(bp): 18693101



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing//Data Mining
Description:A total of 22 tsRNAs were differentially expressed in the three groups. Three selected tsRNAs were validated by quantitative real-time PCR for further analysis, which were all significantly overexpressed in DFU while being normally expressed after HBO treatment.
Comparision:DFU VS Normal
Mechanism:Data Mining disclosed that these tsRNAs may play therapeutic roles through the regulation of the Wnt signaling pathway.