Entry Detail


General Information

Database ID:TRD04022
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-31-79MP9P9NH57SD
tsRNA Type:tRF-5
Amino acid and Anticodon:ValAAC;ValCAC
Sequence:GTTTCCGTAGTGTAGTGGTTATCACGTTCGC
Related Target:N/A
Predicted Target:SLC12A5//CTNND2//CLSTN3//TNFRSF10B//CLPB//SREBF2//RABGAP1//OPLAH//FAM171A1//NLRC5
External Links:
MINTbase ID:tRF-31-79MP9P9NH57SD
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Val-AAC-4-1
Anticodon:ValAAC
tRNA_number:trna136
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27648927        End Site(bp): 27648957

[2] gtRNAdb_ID:tRNA-Val-AAC-3-1
Anticodon:ValAAC
tRNA_number:trna139
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27618749        End Site(bp): 27618779

[3] gtRNAdb_ID:tRNA-Val-AAC-1-1
Anticodon:ValAAC
tRNA_number:trna2
Chromosome:3
Strand:+
Coordinate:Start Site(bp): 169490018        End Site(bp): 169490048

[4] gtRNAdb_ID:tRNA-Val-AAC-1-4
Anticodon:ValAAC
tRNA_number:trna12
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180645312        End Site(bp): 180645342

[5] gtRNAdb_ID:tRNA-Val-AAC-1-2
Anticodon:ValAAC
tRNA_number:trna4
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180591154        End Site(bp): 180591184

[6] gtRNAdb_ID:tRNA-Val-AAC-1-3
Anticodon:ValAAC
tRNA_number:trna5
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180596610        End Site(bp): 180596640

[7] gtRNAdb_ID:tRNA-Val-AAC-1-5
Anticodon:ValAAC
tRNA_number:trna132
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27721221        End Site(bp): 27721251

[8] gtRNAdb_ID:tRNA-Val-CAC-5-1
Anticodon:ValCAC
tRNA_number:trna90
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149684131        End Site(bp): 149684161

[9] gtRNAdb_ID:tRNA-Val-CAC-4-1
Anticodon:ValCAC
tRNA_number:trna98
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149298597        End Site(bp): 149298627

[10] gtRNAdb_ID:tRNA-Val-CAC-1-1
Anticodon:ValCAC
tRNA_number:trna85
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161369532        End Site(bp): 161369562

[11] gtRNAdb_ID:tRNA-Val-CAC-1-5
Anticodon:ValCAC
tRNA_number:trna10
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180649437        End Site(bp): 180649467

[12] gtRNAdb_ID:tRNA-Val-CAC-1-3
Anticodon:ValCAC
tRNA_number:trna18
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180529295        End Site(bp): 180529325

[13] gtRNAdb_ID:tRNA-Val-CAC-1-2
Anticodon:ValCAC
tRNA_number:trna2
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180524070        End Site(bp): 180524100

[14] gtRNAdb_ID:tRNA-Val-CAC-1-4
Anticodon:ValCAC
tRNA_number:trna6
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180600650        End Site(bp): 180600680

[15] gtRNAdb_ID:tRNA-Val-CAC-1-6
Anticodon:ValCAC
tRNA_number:trna9
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26538282        End Site(bp): 26538312



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A