Entry Detail


General Information

Database ID:TRD03861
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-16-6S7P4PE
tsRNA Type:tRF-5
Amino acid and Anticodon:SerACT;IleAAT;IleGAT
Sequence:GGCCGGTTAGCTCAGT
Related Target:N/A
Predicted Target:SRSF8//CELSR2//CILP//PIEZO1//TYSND1//MARCOL//SIAH3//SLC7A14//PHLDB1//RABL6
External Links:
MINTbase ID:tRF-16-6S7P4PE
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Ser-ACT-1-1
Anticodon:SerACT
tRNA_number:trna41
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27261671        End Site(bp): 27261686

[2] gtRNAdb_ID:tRNA-Ile-AAT-8-1
Anticodon:IleAAT
tRNA_number:trna57
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27636362        End Site(bp): 27636377

[3] gtRNAdb_ID:tRNA-Ile-AAT-7-1
Anticodon:IleAAT
tRNA_number:trna165
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 26721279        End Site(bp): 26721294

[4] gtRNAdb_ID:tRNA-Ile-AAT-7-2
Anticodon:IleAAT
tRNA_number:trna28
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26780832        End Site(bp): 26780847

[5] gtRNAdb_ID:tRNA-Ile-AAT-6-1
Anticodon:IleAAT
tRNA_number:trna163
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 26745313        End Site(bp): 26745328

[6] gtRNAdb_ID:tRNA-Ile-AAT-5-4
Anticodon:IleAAT
tRNA_number:trna10
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 102783429        End Site(bp): 102783444

[7] gtRNAdb_ID:tRNA-Ile-AAT-5-5
Anticodon:IleAAT
tRNA_number:trna9
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8090911        End Site(bp): 8090926

[8] gtRNAdb_ID:tRNA-Ile-AAT-5-1
Anticodon:IleAAT
tRNA_number:trna11
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26554350        End Site(bp): 26554365

[9] gtRNAdb_ID:tRNA-Ile-AAT-5-3
Anticodon:IleAAT
tRNA_number:trna154
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27205408        End Site(bp): 27205423

[10] gtRNAdb_ID:tRNA-Ile-AAT-5-2
Anticodon:IleAAT
tRNA_number:trna158
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27145052        End Site(bp): 27145067

[11] gtRNAdb_ID:tRNA-Ile-AAT-4-1
Anticodon:IleAAT
tRNA_number:trna34
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8130367        End Site(bp): 8130382

[12] gtRNAdb_ID:tRNA-Ile-AAT-2-1
Anticodon:IleAAT
tRNA_number:trna59
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27655967        End Site(bp): 27655982

[13] gtRNAdb_ID:tRNA-Ile-AAT-1-1
Anticodon:IleAAT
tRNA_number:trna80
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 58149254        End Site(bp): 58149269

[14] gtRNAdb_ID:tRNA-Ile-GAT-1-3
Anticodon:IleGAT
tRNA_number:trna5
Chromosome:X
Strand:-
Coordinate:Start Site(bp): 3833329        End Site(bp): 3833344

[15] gtRNAdb_ID:tRNA-Ile-GAT-1-2
Anticodon:IleGAT
tRNA_number:trna6
Chromosome:X
Strand:-
Coordinate:Start Site(bp): 3794900        End Site(bp): 3794915

[16] gtRNAdb_ID:tRNA-Ile-GAT-1-1
Anticodon:IleGAT
tRNA_number:trna7
Chromosome:X
Strand:-
Coordinate:Start Site(bp): 3756476        End Site(bp): 3756491



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A