Entry Detail


General Information

Database ID:TRD03826
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-18-6978WPDY
tsRNA Type:tRF-5
Amino acid and Anticodon:ProAGG;ProCGG;ProTGG
Sequence:GGCTCGTTGGTCTAGGGG
Related Target:N/A
Predicted Target:ANKRD10//SH3GL1//PTPRU//KCNJ4//NEK8//SMPD3//CAB39L//WASHC1//FBXO24//MORC2
External Links:
MINTbase ID:tRF-18-6978WPDY
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Pro-AGG-2-1
Anticodon:ProAGG
tRNA_number:trna65
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 167684779        End Site(bp): 167684796

[2] gtRNAdb_ID:tRNA-Pro-AGG-2-4
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:11
Strand:+
Coordinate:Start Site(bp): 75946557        End Site(bp): 75946574

[3] gtRNAdb_ID:tRNA-Pro-AGG-2-6
Anticodon:ProAGG
tRNA_number:trna22
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21081614        End Site(bp): 21081631

[4] gtRNAdb_ID:tRNA-Pro-AGG-2-5
Anticodon:ProAGG
tRNA_number:trna23
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21077549        End Site(bp): 21077566

[5] gtRNAdb_ID:tRNA-Pro-AGG-2-7
Anticodon:ProAGG
tRNA_number:trna29
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3232689        End Site(bp): 3232706

[6] gtRNAdb_ID:tRNA-Pro-AGG-2-8
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3239634        End Site(bp): 3239651

[7] gtRNAdb_ID:tRNA-Pro-AGG-2-2
Anticodon:ProAGG
tRNA_number:trna12
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26555498        End Site(bp): 26555515

[8] gtRNAdb_ID:tRNA-Pro-AGG-2-3
Anticodon:ProAGG
tRNA_number:trna2
Chromosome:7
Strand:+
Coordinate:Start Site(bp): 128423504        End Site(bp): 128423521

[9] gtRNAdb_ID:tRNA-Pro-AGG-1-1
Anticodon:ProAGG
tRNA_number:trna11
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3241989        End Site(bp): 3242006

[10] gtRNAdb_ID:tRNA-Pro-CGG-2-1
Anticodon:ProCGG
tRNA_number:trna30
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27059521        End Site(bp): 27059538

[11] gtRNAdb_ID:tRNA-Pro-CGG-1-1
Anticodon:ProCGG
tRNA_number:trna52
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 167683962        End Site(bp): 167683979

[12] gtRNAdb_ID:tRNA-Pro-CGG-1-2
Anticodon:ProCGG
tRNA_number:trna6
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3222049        End Site(bp): 3222066

[13] gtRNAdb_ID:tRNA-Pro-CGG-1-3
Anticodon:ProCGG
tRNA_number:trna37
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8126205        End Site(bp): 8126222

[14] gtRNAdb_ID:tRNA-Pro-TGG-3-2
Anticodon:ProTGG
tRNA_number:trna6
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21152175        End Site(bp): 21152192

[15] gtRNAdb_ID:tRNA-Pro-TGG-3-4
Anticodon:ProTGG
tRNA_number:trna28
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3234187        End Site(bp): 3234204

[16] gtRNAdb_ID:tRNA-Pro-TGG-3-3
Anticodon:ProTGG
tRNA_number:trna3
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3208923        End Site(bp): 3208940

[17] gtRNAdb_ID:tRNA-Pro-TGG-3-5
Anticodon:ProTGG
tRNA_number:trna8
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3238094        End Site(bp): 3238111

[18] gtRNAdb_ID:tRNA-Pro-TGG-3-1
Anticodon:ProTGG
tRNA_number:trna14
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180615908        End Site(bp): 180615925

[19] gtRNAdb_ID:tRNA-Pro-TGG-2-1
Anticodon:ProTGG
tRNA_number:trna12
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 75946923        End Site(bp): 75946940

[20] gtRNAdb_ID:tRNA-Pro-AGG-3-1
Anticodon:ProAGG
tRNA_number:trna4
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3210386        End Site(bp): 3210403



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015451DOID:1040
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cellchronic lymphocytic leukemia
Category:MeSHDisease Ontology
Type:Neoplasms//Hemic and Lymphatic Diseases//Immune System Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity//disease of cellular proliferation
Define:A chronic leukemia characterized by abnormal B-lymphocytes and often generalized lymphadenopathy. In patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia (CLL); in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. These terms represent spectrums of the same disease.A lymphocytic leukemia characterized by over production of B-cells and their accumulation in bone marrow and blood.
Alias:B-Cell Chronic Lymphocytic Leukemia//B-Cell Leukemia, Chronic//B-Cell Malignancy, Low-Grade//B-Lymphocytic Leukemia, Chronic//Chronic Lymphocytic Leukemia//Diffuse Well-Differentiated Lymphocytic Lymphoma//Disrupted In B-Cell Malignancy//Leukemia, B Cell, Chronic//Leukemia, B-Cell, Chronic//Leukemia, Chronic Lymphatic//Leukemia, Chronic Lymphocytic//Leukemia, Chronic Lymphocytic, B-Cell//Leukemia, Lymphoblastic, Chronic//Leukemia, Lymphocytic, Chronic//Leukemia, Lymphocytic, Chronic, B Cell//Lymphoblastic Leukemia, Chronic//Lymphocytic Leukemia, Chronic//Lymphocytic Leukemia, Chronic, B Cell//Lymphocytic Leukemia, Chronic, B-Cell//Lymphocytic Lymphoma//Lymphocytic Lymphoma, Diffuse, Well Differentiated//Lymphocytic Lymphoma, Diffuse, Well-Differentiated//Lymphocytic Lymphoma, Well Differentiated//Lymphocytic Lymphoma, Well-Differentiated//Lymphoma, Lymphocytic//Lymphoma, Lymphocytic, Diffuse, Well Differentiated//Lymphoma, Lymphocytic, Diffuse, Well-Differentiated//Lymphoma, Lymphocytic, Well Differentiated//Lymphoma, Lymphocytic, Well-Differentiated//Lymphoma, Lymphoplasmacytoid, CLL//Lymphoma, Small Lymphocytic//Lymphoma, Small Lymphocytic, Plasmacytoid//Lymphoma, Small-Cell//Lymphoplasmacytoid Lymphoma, CLL//Small-Cell LymphomaB-cell chronic lymphocytic leukaemia//B-cell chronic lymphocytic leukemia//B-cell chronic lymphoid leukemia//chronic lymphatic leukaemia//chronic lymphatic leukemia//chronic lymphocytic leukaemia//CLL//lymphoplasmacytic leukaemia//lymphoplasmacytic leukemia



Disease Association Statistics

Total Associated tsRNA Number:1731
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31723042
Disease Name:Leukemia, Lymphocytic, Chronic, B-Cell
Tissue:Chronic Lymphocytic Leukemia
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:We identified tsRNA signatures in aggressive and indolent CLL. We further analyzed the expression of mature tRFs and found that mature tRFs are drastically dysregulated in CLL.
Comparision:Cancer VS Normal
Mechanism:N/A