Entry Detail


General Information

Database ID:TRD03815
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Pro-AGG-006
tsRNA Type:tRF-5
Amino acid and Anticodon:ProAGG
Sequence:GGCTCGTTGGTCTAGGGGTATGATTCTCGCTT
Related Target:N/A
Predicted Target:KCNJ4//STAB2//NOMO2//NOMO3//BLMH//HMGN2//KEAP1//LEMD3//PRDM7//NOG
External Links:
MINTbase ID:tRF-32-6978WPRLXN4VQ
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Pro-AGG-2-1
Anticodon:ProAGG
tRNA_number:trna65
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 167684765        End Site(bp): 167684796

[2] gtRNAdb_ID:tRNA-Pro-AGG-2-4
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:11
Strand:+
Coordinate:Start Site(bp): 75946557        End Site(bp): 75946588

[3] gtRNAdb_ID:tRNA-Pro-AGG-2-6
Anticodon:ProAGG
tRNA_number:trna22
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21081600        End Site(bp): 21081631

[4] gtRNAdb_ID:tRNA-Pro-AGG-2-5
Anticodon:ProAGG
tRNA_number:trna23
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21077535        End Site(bp): 21077566

[5] gtRNAdb_ID:tRNA-Pro-AGG-2-7
Anticodon:ProAGG
tRNA_number:trna29
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3232675        End Site(bp): 3232706

[6] gtRNAdb_ID:tRNA-Pro-AGG-2-8
Anticodon:ProAGG
tRNA_number:trna9
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3239634        End Site(bp): 3239665

[7] gtRNAdb_ID:tRNA-Pro-AGG-2-2
Anticodon:ProAGG
tRNA_number:trna12
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26555498        End Site(bp): 26555529

[8] gtRNAdb_ID:tRNA-Pro-AGG-2-3
Anticodon:ProAGG
tRNA_number:trna2
Chromosome:7
Strand:+
Coordinate:Start Site(bp): 128423504        End Site(bp): 128423535

[9] gtRNAdb_ID:tRNA-Pro-AGG-1-1
Anticodon:ProAGG
tRNA_number:trna11
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3241989        End Site(bp): 3242020

[10] gtRNAdb_ID:tRNA-Pro-CGG-2-1
Anticodon:ProCGG
tRNA_number:trna30
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27059521        End Site(bp): 27059552

[11] gtRNAdb_ID:tRNA-Pro-CGG-1-1
Anticodon:ProCGG
tRNA_number:trna52
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 167683962        End Site(bp): 167683993

[12] gtRNAdb_ID:tRNA-Pro-CGG-1-2
Anticodon:ProCGG
tRNA_number:trna6
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3222049        End Site(bp): 3222080

[13] gtRNAdb_ID:tRNA-Pro-CGG-1-3
Anticodon:ProCGG
tRNA_number:trna37
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8126191        End Site(bp): 8126222

[14] gtRNAdb_ID:tRNA-Pro-TGG-3-2
Anticodon:ProTGG
tRNA_number:trna6
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21152175        End Site(bp): 21152206

[15] gtRNAdb_ID:tRNA-Pro-TGG-3-4
Anticodon:ProTGG
tRNA_number:trna28
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3234173        End Site(bp): 3234204

[16] gtRNAdb_ID:tRNA-Pro-TGG-3-3
Anticodon:ProTGG
tRNA_number:trna3
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3208923        End Site(bp): 3208954

[17] gtRNAdb_ID:tRNA-Pro-TGG-3-5
Anticodon:ProTGG
tRNA_number:trna8
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3238094        End Site(bp): 3238125

[18] gtRNAdb_ID:tRNA-Pro-TGG-3-1
Anticodon:ProTGG
tRNA_number:trna14
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180615894        End Site(bp): 180615925



tsRNA Association Statistics

Total Associated Disease Number:10
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D001943DOID:1612
Disease Name:Breast Neoplasmsbreast cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Skin and Connective Tissue Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the human BREAST.A thoracic cancer that originates in the mammary gland.
Alias:Breast Cancer//Breast Carcinoma//Breast Tumors//Cancer of Breast//Cancer of the Breast//Human Mammary Carcinoma//Malignant Neoplasm of Breast//Malignant Tumor of Breast//Mammary Cancer//Mammary Carcinoma, Human//Mammary Neoplasm, Human//Mammary Neoplasms, Human//Neoplasms, Breast//Tumors, Breastbreast tumor//malignant neoplasm of breast//malignant tumor of the breast//mammary cancer//mammary neoplasm//mammary tumor//primary breast cancer



Disease Association Statistics

Total Associated tsRNA Number:549
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:32814252
Disease Name:Breast Neoplasms
Tissue:Plasma
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:Thirty tRFs and tiRNAs were selected by high-throughput sequencing in screening phase and then assessed in training, testing, and external validation phases byqRT-PCR. Six tRFs (tRF-Glu-CTC-003, tRF-Gly-CCC-007, tRF-Gly-CCC-008, tRF-Leu-CAA-003, tRF-Ser-TGA-001, and tRF-Ser-TGA-002) were found significantly downregulated in plasma samples of patients with EBC compared with normal controls.
Comparision:Cancer VS Normal
Mechanism:N/A