Entry Detail


General Information

Database ID:TRD03813
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-1:29-Pro-AGG-1-M6
tsRNA Type:tRF-5
Amino acid and Anticodon:ProAGG
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:8
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D008175DOID:1324
Disease Name:Lung Neoplasmslung cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Respiratory Tract Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the LUNG.A respiratory system cancer that is located_in the lung.
Alias:Cancer of Lung//Cancer of the Lung//Lung Cancer//Neoplasms, Lung//Neoplasms, Pulmonary//Pulmonary Cancer//Pulmonary Neoplasmslung neoplasm



Disease Association Statistics

Total Associated tsRNA Number:102
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:36203461
Disease Name:Lung Neoplasms
Tissue:Plasma
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:N/A
Comparision:Cancer VS Normal
Mechanism:tRF-55:76-Tyr-GTA-1-M2 was upregulated, which was consistent with the sequencing data. The areas under the receiver operating characteristic curve of tRF-1:29-Pro-AGG-1-M6 and tRF-55:76-Tyr-GTA-1-M2 were 0.882 and 0.896, respectively, which have significant values in the diagnosis of LUAD. The expressions of tRF-1:29-ProAGG-1-M6 and tRF-55:76-Tyr-GTA-1-M2 in LUAD were obviously correlated with various clinicopathological features such as tumor-node-metastasis stage, node stage, and the expression levels of carcinoembryonic antigen.