Entry Detail


General Information

Database ID:TRD03633
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Leu-TAG-002
tsRNA Type:tRF-5
Amino acid and Anticodon:LeuTAG
Sequence:GGTAGTGTGGCCGAGC
Related Target:N/A
Predicted Target:TP73//SORBS1//RUNX1//APOBEC3D//AL022318.4//MARCH4//MRPS2//AATK//SLC39A8//EDIL3
External Links:
MINTbase ID:tRF-16-RP9830D
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Leu-TAG-2-1
Anticodon:LeuTAG
tRNA_number:trna2
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21093529        End Site(bp): 21093544



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 122).
Comparision:DFU VS Normal
Mechanism:N/A