Entry Detail



General Information

Database ID:TRD03614
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Leu-TAA-005
tsRNA Type:tRF-5
Amino acid and Anticodon:LeuTAA
Sequence:ACCAGGATGGCCGAGT
Related Target:N/A
Predicted Target:C6orf201//TENM4//GSTT2B//GSTT2//AQP10//HDAC1//TMEM42//GCGR//MAN2B2//ARL2BP
External Links:
MINTbase ID:tRF-16-0P5830E
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Leu-TAA-1-1
Anticodon:LeuTAA
tRNA_number:trna83
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 144537684        End Site(bp): 144537699



tsRNA Association Statistics

Total Associated Disease Number:11
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D002289DOID:3908
Disease Name:Carcinoma, Non-Small-Cell Lunglung non-small cell carcinoma
Category:MeSHDisease Ontology
Type:Neoplasms//Respiratory Tract Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy.A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma.
Alias:Carcinoma, Non-Small Cell Lung//Non-Small Cell Lung Cancer//Non-Small Cell Lung Carcinoma//Non-Small-Cell Lung Carcinoma//Nonsmall Cell Lung CancerNon-small cell lung cancer//non-small cell lung carcinoma//NSCLC



Disease Association Statistics

Total Associated tsRNA Number:132
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:36387119
Disease Name:Carcinoma, Non-Small-Cell Lung
Tissue:Plasma
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:Our results showed that the levels of exosomal tRF-Leu-TAA005, tRF-Asn-GTT-010, tRF-Ala-AGC-036, tRF-Lys-CTT-049, and tRF-TrpCCA-058 were significantly downregulated in NSCLC patients. This suggests that these five exosomal tRFs may be promising diagnostic biomarkers for NSCLC.
Comparision:Cancer VS Normal
Mechanism:N/A