Entry Detail



General Information

Database ID:TRD03583
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Leu-CAA-004
tsRNA Type:tRF-5
Amino acid and Anticodon:LeuCAA
Sequence:GTCAGGATGGCCGAGT
Related Target:N/A
Predicted Target:GSTT2B//GSTT2//AHRR//C6orf201//SEC13//TENM4//HRH4//HKDC1//COL11A1//LYL1
External Links:
MINTbase ID:tRF-16-SP5830E
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Leu-CAA-3-1
Anticodon:LeuCAA
tRNA_number:trna141
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27570439        End Site(bp): 27570454

[2] gtRNAdb_ID:tRNA-Leu-CAA-2-1
Anticodon:LeuCAA
tRNA_number:trna140
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27573509        End Site(bp): 27573524

[3] gtRNAdb_ID:tRNA-Leu-CAA-1-1
Anticodon:LeuCAA
tRNA_number:trna100
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28864090        End Site(bp): 28864105

[4] gtRNAdb_ID:tRNA-Leu-CAA-1-2
Anticodon:LeuCAA
tRNA_number:trna74
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28908830        End Site(bp): 28908845

[5] gtRNAdb_ID:tRNA-Leu-CAA-4-1
Anticodon:LeuCAA
tRNA_number:trna58
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 249168054        End Site(bp): 249168069



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 112).
Comparision:DFU VS Normal
Mechanism:N/A