Entry Detail


General Information

Database ID:TRD03551
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Leu-AAG-003
tsRNA Type:tRF-5
Amino acid and Anticodon:LeuAAG
Sequence:GGTAGCGTGGCCGAGC
Related Target:N/A
Predicted Target:TP73//MRPS2//RUNX1//SLC39A8//ZMYM2//PTBP1//FBXL22//CDT1//HEXA//TRIL
External Links:
MINTbase ID:tRF-16-RPM830D
tRFdb ID:tRFdb-5019a

[1] gtRNAdb_ID:tRNA-Leu-AAG-3-1
Anticodon:LeuAAG
tRNA_number:trna78
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28956779        End Site(bp): 28956794

[2] gtRNAdb_ID:tRNA-Leu-AAG-2-3
Anticodon:LeuAAG
tRNA_number:trna1
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21078291        End Site(bp): 21078306

[3] gtRNAdb_ID:tRNA-Leu-AAG-2-4
Anticodon:LeuAAG
tRNA_number:trna16
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 22308461        End Site(bp): 22308476

[4] gtRNAdb_ID:tRNA-Leu-AAG-2-1
Anticodon:LeuAAG
tRNA_number:trna7
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180614701        End Site(bp): 180614716

[5] gtRNAdb_ID:tRNA-Leu-AAG-2-2
Anticodon:LeuAAG
tRNA_number:trna98
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28911465        End Site(bp): 28911480

[6] gtRNAdb_ID:tRNA-Leu-AAG-1-3
Anticodon:LeuAAG
tRNA_number:trna16
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180601110        End Site(bp): 180601125

[7] gtRNAdb_ID:tRNA-Leu-AAG-1-1
Anticodon:LeuAAG
tRNA_number:trna19
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180524540        End Site(bp): 180524555

[8] gtRNAdb_ID:tRNA-Leu-AAG-1-2
Anticodon:LeuAAG
tRNA_number:trna3
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180528840        End Site(bp): 180528855

[9] gtRNAdb_ID:tRNA-Leu-TAG-1-1
Anticodon:LeuTAG
tRNA_number:trna42
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8023698        End Site(bp): 8023713



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 133).
Comparision:DFU VS Normal
Mechanism:N/A