Entry Detail


General Information

Database ID:TRD03415
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRNA-Gly-GCC-1-4
tsRNA Type:tRF-5
Amino acid and Anticodon:GlyGCC
Sequence:GCATGGGTGGTTCAGTGGTAG
Related Target:N/A
Predicted Target:FCGR2A//HSD17B4//TNS2//DDI1//EIF3G//SORCS1//PRELP//CDC16//CDCP2//AL357673.1
External Links:
MINTbase ID:tRF-21-P4R8YP9L0
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-GCC-1-1
Anticodon:GlyGCC
tRNA_number:trna35
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161413094        End Site(bp): 161413114

[2] gtRNAdb_ID:tRNA-Gly-GCC-1-2
Anticodon:GlyGCC
tRNA_number:trna37
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161420467        End Site(bp): 161420487

[3] gtRNAdb_ID:tRNA-Gly-GCC-1-3
Anticodon:GlyGCC
tRNA_number:trna39
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161427898        End Site(bp): 161427918

[4] gtRNAdb_ID:tRNA-Gly-GCC-1-4
Anticodon:GlyGCC
tRNA_number:trna41
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161435258        End Site(bp): 161435278

[5] gtRNAdb_ID:tRNA-Gly-GCC-1-5
Anticodon:GlyGCC
tRNA_number:trna2
Chromosome:21
Strand:-
Coordinate:Start Site(bp): 18827157        End Site(bp): 18827177



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D001943DOID:1612
Disease Name:Breast Neoplasmsbreast cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Skin and Connective Tissue Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the human BREAST.A thoracic cancer that originates in the mammary gland.
Alias:Breast Cancer//Breast Carcinoma//Breast Tumors//Cancer of Breast//Cancer of the Breast//Human Mammary Carcinoma//Malignant Neoplasm of Breast//Malignant Tumor of Breast//Mammary Cancer//Mammary Carcinoma, Human//Mammary Neoplasm, Human//Mammary Neoplasms, Human//Neoplasms, Breast//Tumors, Breastbreast tumor//malignant neoplasm of breast//malignant tumor of the breast//mammary cancer//mammary neoplasm//mammary tumor//primary breast cancer



Disease Association Statistics

Total Associated tsRNA Number:549
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:35030975
Disease Name:Breast Neoplasms
Tissue:Breast
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:As shown in Figure 1(c), tRNA-Lys-TTT-3-1, tRNA-Gly-GCC-1-4, tRNA-Ser-AGA-2-5 and tRNA-Ser-AGA-3-1 (tRF-19-W4PU732S) were significantly up-regulated in BC compared to the control, and the survival time of BC patients with high expression was lower than that of BC patients with low expression, whereas tRNA-His-GTG-1-1 showed lower expression and was associated with good prognosis.
Comparision:Cancer VS Normal
Mechanism:N/A