Entry Detail


General Information

Database ID:TRD03341
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-000690
tsRNA Type:tRF-5
Amino acid and Anticodon:GlyGCC
Sequence:GCATTGGTGGTTCAGTGGTAGAATTCT
Related Target:N/A
Predicted Target:FCGR2A//OLFM3//AGBL3//PRELP//TUBGCP3//CSPG4//ZNF592//MUCL1//PCGF5//MRRF
External Links:
MINTbase ID:tRF-27-PNR8YP9LON3
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-CCC-1-1
Anticodon:GlyCCC
tRNA_number:trna133
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16872478        End Site(bp): 16872504

[2] gtRNAdb_ID:tRNA-Gly-CCC-1-2
Anticodon:GlyCCC
tRNA_number:trna4
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17188416        End Site(bp): 17188442

[3] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822597        End Site(bp): 70822623

[4] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812158        End Site(bp): 70812184

[5] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493681        End Site(bp): 161493707

[6] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823410        End Site(bp): 70823436

[7] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812986        End Site(bp): 70813012

[8] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029064        End Site(bp): 8029090

[9] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257703        End Site(bp): 157257729

[10] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870730        End Site(bp): 27870756



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A