Entry Detail


General Information

Database ID:TRD03336
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:5'tRF-Gly-GCC
tsRNA Type:tRF-5
Amino acid and Anticodon:GlyGCC
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:4
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D007248DOID:12336
Disease Name:Infertility, Malemale infertility
Category:MeSHDisease Ontology
Type:Urogenital Diseasesdisease of anatomical entity
Define:The inability of the male to effect FERTILIZATION of an OVUM after a specified period of unprotected intercourse. Male sterility is permanent infertility.N/A
Alias:Sterility, Male//Sub-Fertility, Male//Subfertility, MaleN/A



Disease Association Statistics

Total Associated tsRNA Number:26
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:33693947
Disease Name:Infertility, Male
Tissue:Seminal Plasma
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:The results obtained demonstrated that levels of 5'tRF-Glu-CTC, 5’tRF-Lys-CTT, and 6’tRF-Gly-GCC are significantly elevated in seminal samples from cases with repeated failed ICSI cycles, suggesting a potential association between increased seminal tRFs and unexplained male infertility.
Comparision:Disease VS Control
Mechanism:N/A