Entry Detail



General Information

Database ID:TRD03317
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-19-PNR8YPJZ
tsRNA Type:tRF-5
Amino acid and Anticodon:GlyCCC;GlyGCC
Sequence:GCATTGGTGGTTCAGTGGT
Related Target:AXIN2
Predicted Target:FCGR2A//ERAS//ZG16B//GTF3C2//KLC1//ADAR//PRELP//ZNF526//TRRAP//ATP1B1
External Links:
MINTbase ID:tRF-19-PNR8YPJZ
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-CCC-1-1
Anticodon:GlyCCC
tRNA_number:trna133
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16872486        End Site(bp): 16872504

[2] gtRNAdb_ID:tRNA-Gly-CCC-1-2
Anticodon:GlyCCC
tRNA_number:trna4
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17188416        End Site(bp): 17188434

[3] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822597        End Site(bp): 70822615

[4] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812166        End Site(bp): 70812184

[5] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493689        End Site(bp): 161493707

[6] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823410        End Site(bp): 70823428

[7] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812994        End Site(bp): 70813012

[8] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029064        End Site(bp): 8029082

[9] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257711        End Site(bp): 157257729

[10] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870738        End Site(bp): 27870756



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D010190DOID:1793
Disease Name:Pancreatic Neoplasmspancreatic cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseases//Endocrine System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).An endocrine gland cancer located_in the pancreas.
Alias:Cancer of Pancreas//Cancer of the Pancreas//Neoplasms, Pancreatic//Pancreas Cancer//Pancreas Neoplasms//Pancreatic CancerCa body of pancreas//Ca head of pancreas//Ca tail of pancreas//malignant neoplasm of body of pancreas//malignant neoplasm of head of pancreas//malignant neoplasm of tail of pancreas pancreas neoplasm [EXACT] pancreatic neoplasm [EXACT] pancreatic tumor [EXACT]



Disease Association Statistics

Total Associated tsRNA Number:112
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37488774
Disease Name:Pancreatic Neoplasms
Tissue:PC And Corresponding Adjacent Non-Tumour Tissues
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:PC tissue samples showed markedly higher levels of tRF-19-PNR8YPJZ than normal controls.
Comparision:Tumor VS Normal
Mechanism:Exosomal tRF-19-PNR8YPJZ from PSCs promoted proliferation and metastasis in PC cells via AXIN2.