Entry Detail


General Information

Database ID:TRD03164
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Glu-CTC-017
tsRNA Type:tRF-5
Amino acid and Anticodon:GluCTC
Sequence:TCCCTGGTGGTCTAGTGGTTAGGA
Related Target:N/A
Predicted Target:TFCP2L1//CHRNA1//TUBA1B//EME2//QSER1//SLC25A48//ARMCX4//RBM28//EHMT1//INSYN1
External Links:
MINTbase ID:tRF-24-87R8WP9NEX
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Glu-CTC-2-1
Anticodon:GluCTC
tRNA_number:trna59
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 249168447        End Site(bp): 249168470

[2] gtRNAdb_ID:tRNA-Glu-CTC-1-1
Anticodon:GluCTC
tRNA_number:trna116
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145399281        End Site(bp): 145399304

[3] gtRNAdb_ID:tRNA-Glu-CTC-1-5
Anticodon:GluCTC
tRNA_number:trna71
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161439237        End Site(bp): 161439260

[4] gtRNAdb_ID:tRNA-Glu-CTC-1-4
Anticodon:GluCTC
tRNA_number:trna74
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161431857        End Site(bp): 161431880

[5] gtRNAdb_ID:tRNA-Glu-CTC-1-3
Anticodon:GluCTC
tRNA_number:trna77
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161424446        End Site(bp): 161424469

[6] gtRNAdb_ID:tRNA-Glu-CTC-1-2
Anticodon:GluCTC
tRNA_number:trna80
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161417066        End Site(bp): 161417089

[7] gtRNAdb_ID:tRNA-Glu-CTC-1-6
Anticodon:GluCTC
tRNA_number:trna77
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28949976        End Site(bp): 28949999

[8] gtRNAdb_ID:tRNA-Glu-CTC-1-7
Anticodon:GluCTC
tRNA_number:trna87
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 126101441        End Site(bp): 126101464



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D009914DOID:5773
Disease Name:Oral Submucous Fibrosisoral submucous fibrosis
Category:MeSHDisease Ontology
Type:Stomatognathic Diseasesdisease of anatomical entity
Define:Irreversible FIBROSIS of the submucosal tissue of the MOUTH.A mouth disease that is characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues.
Alias:N/AOral cavity Submucous Fibrosis//Oral submucosal fibrosis//Oral submucosal fibrosis, including of tongue



Disease Association Statistics

Total Associated tsRNA Number:126
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:34558114
Disease Name:Oral Submucous Fibrosis
Tissue:Oral Submucous Fibrosis
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:Of 126 tsRNAs in OSF were dysregulated, including 73 upregulated tsRNAs and 53 downregulated tsRNAs. The downregulated tiRNA-Val-CAC-002,tRF-Asn-GTT-005, tRF-Trp-CCA-007 and upregulated tRF-Gly-TCC-016,tRF-Pro-TGG-009 showed significant differences by qRT-PCR validation.
Comparision:Disease VS Control
Mechanism:tRNA-derived fragments are dysregulated and could be involved in the pathogenesis of oral submucous fibrosis.