Entry Detail


General Information

Database ID:TRD02919
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-16-R29P4PE
tsRNA Type:tRF-5
Amino acid and Anticodon:AlaAGC;AlaCGC;AlaTGC
Sequence:GGGGATGTAGCTCAGT
Related Target:N/A
Predicted Target:GPR84//CDK10//FARP1//C1orf94//WDR55//SGSM2//ENAH//DNASE1L3//GATA1//DYRK2
External Links:
MINTbase ID:tRF-16-R29P4PE
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Ala-AGC-4-1
Anticodon:AlaAGC
tRNA_number:trna120
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28626070        End Site(bp): 28626085

[2] gtRNAdb_ID:tRNA-Ala-CGC-3-1
Anticodon:AlaCGC
tRNA_number:trna13
Chromosome:2
Strand:+
Coordinate:Start Site(bp): 157257281        End Site(bp): 157257296

[3] gtRNAdb_ID:tRNA-Ala-CGC-2-1
Anticodon:AlaCGC
tRNA_number:trna119
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28641669        End Site(bp): 28641684

[4] gtRNAdb_ID:tRNA-Ala-CGC-1-1
Anticodon:AlaCGC
tRNA_number:trna10
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26553731        End Site(bp): 26553746

[5] gtRNAdb_ID:tRNA-Ala-TGC-4-1
Anticodon:AlaTGC
tRNA_number:trna8
Chromosome:12
Strand:+
Coordinate:Start Site(bp): 125424512        End Site(bp): 125424527

[6] gtRNAdb_ID:tRNA-Ala-TGC-3-2
Anticodon:AlaTGC
tRNA_number:trna13
Chromosome:12
Strand:-
Coordinate:Start Site(bp): 125406357        End Site(bp): 125406372

[7] gtRNAdb_ID:tRNA-Ala-TGC-3-1
Anticodon:AlaTGC
tRNA_number:trna8
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180633868        End Site(bp): 180633883

[8] gtRNAdb_ID:tRNA-Ala-TGC-2-1
Anticodon:AlaTGC
tRNA_number:trna66
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28611222        End Site(bp): 28611237



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006332N/A
Disease Name:CardiomegalyN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Pathological Conditions, Signs and SymptomsN/A
Define:Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.N/A
Alias:Cardiac Hypertrophy//Enlarged Heart//Heart Enlargement//Heart HypertrophyN/A



Disease Association Statistics

Total Associated tsRNA Number:68
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37370960
Disease Name:Cardiomegaly
Tissue:Plasma
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:As shown in Figure 3A, the expression levels of tRF-30-3JVIJMRPFQ5D, tRF-16-R29P4PE, tRF-21-NB8PLML3E, and tRF-21-SWRYVMMV0 were significantly downregulated (p < 0.05 or p < 0.01).
Comparision:Disease VS Control
Mechanism:N/A