Entry Detail


General Information

Database ID:TRD02911
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Ala-AGC-047
tsRNA Type:tRF-5
Amino acid and Anticodon:AlaAGC
Sequence:GGGGGTGTAGCTCAGT
Related Target:N/A
Predicted Target:ENAH//PIK3R2//MFSD2B//PRKDC//GPR84//DUSP10//SLC4A11//RHOD//CDK10//TRIM10
External Links:
MINTbase ID:tRF-16-RK9P4PE
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Ala-AGC-7-1
Anticodon:AlaAGC
tRNA_number:trna68
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28687481        End Site(bp): 28687496

[2] gtRNAdb_ID:tRNA-Ala-AGC-5-1
Anticodon:AlaAGC
tRNA_number:trna67
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28678366        End Site(bp): 28678381

[3] gtRNAdb_ID:tRNA-Ala-AGC-3-1
Anticodon:AlaAGC
tRNA_number:trna65
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28574933        End Site(bp): 28574948

[4] gtRNAdb_ID:tRNA-Ala-AGC-2-2
Anticodon:AlaAGC
tRNA_number:trna101
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28831518        End Site(bp): 28831533

[5] gtRNAdb_ID:tRNA-Ala-AGC-2-1
Anticodon:AlaAGC
tRNA_number:trna102
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28806277        End Site(bp): 28806292

[6] gtRNAdb_ID:tRNA-Ala-CGC-4-1
Anticodon:AlaCGC
tRNA_number:trna70
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28697092        End Site(bp): 28697107

[7] gtRNAdb_ID:tRNA-Ala-TGC-8-1
Anticodon:AlaTGC
tRNA_number:trna18
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 50233935        End Site(bp): 50233950

[8] gtRNAdb_ID:tRNA-Ala-TGC-7-1
Anticodon:AlaTGC
tRNA_number:trna107
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28770632        End Site(bp): 28770647

[9] gtRNAdb_ID:tRNA-Ala-TGC-6-1
Anticodon:AlaTGC
tRNA_number:trna113
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28726197        End Site(bp): 28726212

[10] gtRNAdb_ID:tRNA-Ala-TGC-5-1
Anticodon:AlaTGC
tRNA_number:trna104
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28785068        End Site(bp): 28785083

[11] gtRNAdb_ID:tRNA-Ala-TGC-1-1
Anticodon:AlaTGC
tRNA_number:trna110
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28757603        End Site(bp): 28757618

[12] gtRNAdb_ID:tRNA-Cys-GCA-6-1
Anticodon:CysGCA
tRNA_number:trna7
Chromosome:3
Strand:-
Coordinate:Start Site(bp): 131948000        End Site(bp): 131948015

[13] gtRNAdb_ID:tRNA-Val-AAC-6-1
Anticodon:ValAAC
tRNA_number:trna115
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28703262        End Site(bp): 28703277



tsRNA Association Statistics

Total Associated Disease Number:7
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D001943DOID:1612
Disease Name:Breast Neoplasmsbreast cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Skin and Connective Tissue Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the human BREAST.A thoracic cancer that originates in the mammary gland.
Alias:Breast Cancer//Breast Carcinoma//Breast Tumors//Cancer of Breast//Cancer of the Breast//Human Mammary Carcinoma//Malignant Neoplasm of Breast//Malignant Tumor of Breast//Mammary Cancer//Mammary Carcinoma, Human//Mammary Neoplasm, Human//Mammary Neoplasms, Human//Neoplasms, Breast//Tumors, Breastbreast tumor//malignant neoplasm of breast//malignant tumor of the breast//mammary cancer//mammary neoplasm//mammary tumor//primary breast cancer



Disease Association Statistics

Total Associated tsRNA Number:549
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:32814252
Disease Name:Breast Neoplasms
Tissue:Plasma
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:Thirty tRFs and tiRNAs were selected by high-throughput sequencing in screening phase and then assessed in training, testing, and external validation phases byqRT-PCR. Six tRFs (tRF-Glu-CTC-003, tRF-Gly-CCC-007, tRF-Gly-CCC-008, tRF-Leu-CAA-003, tRF-Ser-TGA-001, and tRF-Ser-TGA-002) were found significantly downregulated in plasma samples of patients with EBC compared with normal controls.
Comparision:Cancer VS Normal
Mechanism:N/A