tsRNADisease

Entry Detail

General Information

Database ID:	TRD02879
Confidence:	Median
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

miR-1280

tsRNA Type:

tRF-3

Amino acid and Anticodon:

N/A

Sequence:

N/A

Related Target:

Predicted Target:

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	3 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D015179	DOID:9256
Disease Name:	Colorectal Neoplasms	colorectal cancer
Category:	MeSH	Disease Ontology
Type:	Neoplasms//Digestive System Diseases	disease of anatomical entity//disease of cellular proliferation
Define:	Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.	A large intestine cancer that is located_in the colon and/or located_in the rectum.
Alias:	Colorectal Cancer//Colorectal Carcinoma//Colorectal Tumors//Neoplasms, Colorectal	N/A

Disease Association Statistics

Total Associated tsRNA Number:	195 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	N/A
Weak Evidence:	High-throughput sequencing

Reference

[1] PubMed ID:	32195016
Disease Name:	Colorectal Neoplasms
Tissue:	Plasma
Dysfunction Pattern:	Down-Regulation
Validated Method:	High-throughput sequencing
Description:	N/A
Comparision:	Cancer VS Normal
Mechanism:	tRF/miR-1280 may target the Notchligand JAG2 and consequently inhibit cancerstem cell phenotypes through repressing theexpression of Gata1/3 and miR-200b tran-scriptionally.