Entry Detail


General Information

Database ID:TRD02851
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-3017A
tsRNA Type:tRF-3
Amino acid and Anticodon:ValTAC
Sequence:AGCCCCAGTGGAACCACCA
Related Target:NELL2
Predicted Target:MDC1//GIMAP4//LIN7B//MARCH1//GIGYF2//NFKB1//PLCE1//SV2C//RASAL3//TESMIN
External Links:
MINTbase ID:tRF-19-FRJ4O1E2
tRFdb ID:tRFdb-3017a

[1] gtRNAdb_ID:tRNA-Val-TAC-3-1
Anticodon:ValTAC
tRNA_number:trna6
Chromosome:10
Strand:-
Coordinate:Start Site(bp): 5895674-3        End Site(bp): 5895689

[2] gtRNAdb_ID:tRNA-Val-TAC-2-1
Anticodon:ValTAC
tRNA_number:trna16
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 59318460-3        End Site(bp): 59318475

[3] gtRNAdb_ID:tRNA-Val-TAC-1-1
Anticodon:ValTAC
tRNA_number:trna17
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 59318102-3        End Site(bp): 59318117

[4] gtRNAdb_ID:tRNA-Val-TAC-1-2
Anticodon:ValTAC
tRNA_number:trna4
Chromosome:X
Strand:-
Coordinate:Start Site(bp): 18693029-3        End Site(bp): 18693044



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D013274 DOID:10534
Disease Name:Stomach Neoplasmsstomach cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the STOMACH.A gastrointestinal system cancer that is located_in the stomach.
Alias:Cancer of Stomach//Cancer of the Stomach//Gastric Cancer//Gastric Cancer, Familial Diffuse//Gastric Neoplasms//Neoplasms, Gastric//Neoplasms, Stomach//Stomach Cancergastric cancer//gastric neoplasm



Disease Association Statistics

Total Associated tsRNA Number:79
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:N/A



Reference

[1] PubMed ID:33665159
Disease Name:Stomach Neoplasms
Tissue:GC Tissues;Noncancerous Adjacent Tissues;Gastric Mucosal Epithelial Cell Line
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR
Description:tRF-3017A is abnormally highly expressed, revealed that the upregulated expression of tRF-3017A is associated with lymph node metastasis in GC and demonstrated that tRF-3017A promotes migration and invasion ofGC cell lines.
Comparision:Cancer VS Normal
Mechanism:tRF-3017A promotes GC through regulation of NELL2 in a mechanism similar to miRNA-mediated target gene silencing.