Entry Detail


General Information

Database ID:TRD02720
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-57:76-Tyr-GTA-2-M2
tsRNA Type:tRF-3
Amino acid and Anticodon:TyrGTA
Sequence:GATTCCGGCTCGAAGGACCA
Related Target:N/A
Predicted Target:KLHDC4//GAD2//ARHGAP33//REPIN1//PLEKHA8//ATAD1//TNR//DNMT3A//CCDC106//CHD2
External Links:
MINTbase ID:tRF-20-59MIL0O6
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Tyr-GTA-5-3
Anticodon:TyrGTA
tRNA_number:trna19
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21121258-3        End Site(bp): 21121274

[2] gtRNAdb_ID:tRNA-Tyr-GTA-5-4
Anticodon:TyrGTA
tRNA_number:trna16
Chromosome:14
Strand:-
Coordinate:Start Site(bp): 21131351-3        End Site(bp): 21131367

[3] gtRNAdb_ID:tRNA-Tyr-GTA-5-5
Anticodon:TyrGTA
tRNA_number:trna5
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 21151504        End Site(bp): 21151520+3

[4] gtRNAdb_ID:tRNA-Tyr-GTA-2-1
Anticodon:TyrGTA
tRNA_number:trna2
Chromosome:2
Strand:+
Coordinate:Start Site(bp): 27273722        End Site(bp): 27273738+3

[5] gtRNAdb_ID:tRNA-Tyr-GTA-5-1
Anticodon:TyrGTA
tRNA_number:trna4
Chromosome:8
Strand:+
Coordinate:Start Site(bp): 67025678        End Site(bp): 67025694+3

[6] gtRNAdb_ID:tRNA-Tyr-GTA-5-2
Anticodon:TyrGTA
tRNA_number:trna5
Chromosome:8
Strand:+
Coordinate:Start Site(bp): 67026295        End Site(bp): 67026311+3



tsRNA Association Statistics

Total Associated Disease Number:7
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D015179DOID:9256
Disease Name:Colorectal Neoplasmscolorectal cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.A large intestine cancer that is located_in the colon and/or located_in the rectum.
Alias:Colorectal Cancer//Colorectal Carcinoma//Colorectal Tumors//Neoplasms, ColorectalN/A



Disease Association Statistics

Total Associated tsRNA Number:195
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37389118
Disease Name:Colorectal Neoplasms
Tissue:Colon
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:Differences in tRFs and tiRNAs found in SSLs and NCs were determined under the following conditions: absolute log2 (fold change) ≥ 1.5 and P < 0.05. Under these conditions, we identified 52 upregulated and 28 downregulated tRFs and tiRNAs and have shown them in a hierarchical cluster heatmap (Figure ​(Figure1D1D).
Comparision:SSL VS Normal
Mechanism:N/A