Entry Detail


General Information

Database ID:TRD02562
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Ser-CGA-012
tsRNA Type:tRF-3
Amino acid and Anticodon:SerCGA
Sequence:TCCTGCTCACAGCGCCA
Related Target:N/A
Predicted Target:COQ8B//SPAG17//PRICKLE2//TRIM38//TBC1D15//SMPD2//TMEM184A//IL6R//CUL2//AGRN
External Links:
MINTbase ID:tRF-17-8Y45FV2
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Ser-CGA-3-1
Anticodon:SerCGA
tRNA_number:trna137
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27640229-3        End Site(bp): 27640242

[2] gtRNAdb_ID:tRNA-Ser-CGA-2-1
Anticodon:SerCGA
tRNA_number:trna35
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27177696        End Site(bp): 27177709+3

[3] gtRNAdb_ID:tRNA-Ser-CGA-1-1
Anticodon:SerCGA
tRNA_number:trna41
Chromosome:17
Strand:-
Coordinate:Start Site(bp): 8042199-3        End Site(bp): 8042212



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 129).
Comparision:DFU VS Normal
Mechanism:N/A