Entry Detail


General Information

Database ID:TRD02477
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:3'-tRF-ProTGG-19
tsRNA Type:tRF-3
Amino acid and Anticodon:ProTGG
Sequence:N/A
Related Target:N/A
Predicted Target:N/A
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:8
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006973DOID:10763
Disease Name:Hypertensionhypertension
Category:MeSHDisease Ontology
Type:Cardiovascular Diseasesdisease of anatomical entity
Define:Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.An artery disease characterized by chronic elevated blood pressure in the arteries.
Alias:Blood Pressure, HighHTN//hyperpiesia//hypertensive disease//vascular hypertensive disorder



Disease Association Statistics

Total Associated tsRNA Number:14
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:Transfection//PCR//RT-PCR
Weak Evidence:High-throughput sequencing//High-throughput sequencing



Reference

[1] PubMed ID:33775129
Disease Name:Hypertension
Tissue:N/A
Dysfunction Pattern:N/A
Validated Method:Transfection//PCR//RT-PCR//High-throughput sequencing//High-throughput sequencing
Description:As a proof of concept,we experimentally validated the gene regulatory effect of a 3'-tRF (3'-tRF-ProTGG-19) that was dysregulated in both salt-induced hypertension in rats (P=00.002) and hypertensive nephrosclerosis in humans (P=1.7*10-05).
Comparision:N/A
Mechanism:N/A