Entry Detail



General Information

Database ID:TRD02460
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Phe-GAA-012
tsRNA Type:tRF-3
Amino acid and Anticodon:PheGAA
Sequence:CATCACCCCATAAACACCA
Related Target:N/A
Predicted Target:ZNF630//AHNAK//TMEM8B//PKP3//FADS2//MOB3B//MED1//APEH//FBXO3//KRT1
External Links:
MINTbase ID:tRF-19-J6K6UDE2
tRFdb ID:N/A

[1] gtRNAdb_ID:-
Anticodon:PheGAA
tRNA_number:trnaMT
Chromosome:MT
Strand:+
Coordinate:Start Site(bp): 632        End Site(bp): 647+3



tsRNA Association Statistics

Total Associated Disease Number:23
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006333N/A
Disease Name:Heart FailureN/A
Category:MeSHDisease Ontology
Type:Cardiovascular DiseasesN/A
Define:A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.N/A
Alias:Cardiac Failure//Congestive Heart Failure//Heart Decompensation//Heart Failure, Congestive//Heart Failure, Left-Sided//Heart Failure, Right-Sided//Left-Sided Heart Failure//Myocardial Failure//Right-Sided Heart FailureN/A



Disease Association Statistics

Total Associated tsRNA Number:81
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:37839439
Disease Name:Heart Failure
Tissue:Epicardial Adipose Tissue
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:Of those, a total of 24 tsRNAs were significantly differentially expressed between HF and controls: 17 were upregulated and 7 were downregulated (fold change >1.5, p < 0.05).
Comparision:HF VS Control
Mechanism:N/A