Entry Detail


General Information

Database ID:TRD02311
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Leu-CAA-017
tsRNA Type:tRF-3
Amino acid and Anticodon:LeuCAA
Sequence:TCGAATCCCACTTCTGACACCA
Related Target:N/A
Predicted Target:PTCH1//PCYT2//ALDH1L1//CLSPN//RBM43//NGB//ZNF26//PLN//TAF8//TENM4
External Links:
MINTbase ID:tRF-22-WB86N7O52
tRFdb ID:tRFdb-3012b

[1] gtRNAdb_ID:tRNA-Leu-CAG-2-1
Anticodon:LeuCAG
tRNA_number:trna17
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 57333927        End Site(bp): 57333945+3

[2] gtRNAdb_ID:tRNA-Leu-CAG-2-2
Anticodon:LeuCAG
tRNA_number:trna26
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 57334392-3        End Site(bp): 57334410

[3] gtRNAdb_ID:tRNA-Leu-CAA-3-1
Anticodon:LeuCAA
tRNA_number:trna141
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27570348-3        End Site(bp): 27570366

[4] gtRNAdb_ID:tRNA-Leu-CAA-2-1
Anticodon:LeuCAA
tRNA_number:trna140
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27573417-3        End Site(bp): 27573435

[5] gtRNAdb_ID:tRNA-Leu-CAA-1-1
Anticodon:LeuCAA
tRNA_number:trna100
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28864000-3        End Site(bp): 28864018

[6] gtRNAdb_ID:tRNA-Leu-CAA-1-2
Anticodon:LeuCAA
tRNA_number:trna74
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28908916        End Site(bp): 28908934+3

[7] gtRNAdb_ID:tRNA-Leu-CAA-4-1
Anticodon:LeuCAA
tRNA_number:trna58
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 249168141        End Site(bp): 249168159+3



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D017719N/A
Disease Name:Diabetic FootN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Skin and Connective Tissue Diseases//Endocrine System DiseasesN/A
Define:Common foot problems in persons with DIABETES MELLITUS, caused by any combination of factors such as DIABETIC NEUROPATHIES; PERIPHERAL VASCULAR DISEASES; and INFECTION. With the loss of sensation and poor circulation, injuries and infections often lead to severe foot ulceration, GANGRENE and AMPUTATION, SURGICAL.N/A
Alias:Diabetic Feet//Foot Ulcer, DiabeticN/A



Disease Association Statistics

Total Associated tsRNA Number:277
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing//Data Mining



Reference

[1] PubMed ID:34657473
Disease Name:Diabetic Foot
Tissue:Skin
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing//Data Mining
Description:In addition, 244 tsRNAs were confirmed to be dysregulated in DFU tissues: 178 tsRNAs were upregulated, whereas 66 tsRNAs were downregulated (DFU vs normal; FC >1.5 and p < 0.05; Figure 2D & Supplementary data 243).
Comparision:DFU VS Normal
Mechanism:N/A