Entry Detail


General Information

Database ID:TRD02245
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-000086
tsRNA Type:tRF-3
Amino acid and Anticodon:HisGTG
Sequence:TCCGAGTCACGGCACCA
Related Target:N/A
Predicted Target:IFIT2//TFPI//ZNF850//RPL39L//ERVFRD-1//DMAC2L//STK11//ARSA//AC100868.1//EIF2B1
External Links:
MINTbase ID:tRF-17-8US5652
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-His-GTG-2-1
Anticodon:HisGTG
tRNA_number:trna106
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149155828-3        End Site(bp): 149155841

[2] gtRNAdb_ID:tRNA-His-GTG-1-4
Anticodon:HisGTG
tRNA_number:trna111
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 147774845-3        End Site(bp): 147774858

[3] gtRNAdb_ID:tRNA-His-GTG-1-1
Anticodon:HisGTG
tRNA_number:trna118
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145396881-3        End Site(bp): 145396894

[4] gtRNAdb_ID:tRNA-His-GTG-1-2
Anticodon:HisGTG
tRNA_number:trna16
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 146544831        End Site(bp): 146544844+3

[5] gtRNAdb_ID:tRNA-His-GTG-1-3
Anticodon:HisGTG
tRNA_number:trna21
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 147753529        End Site(bp): 147753542+3

[6] gtRNAdb_ID:tRNA-His-GTG-1-9
Anticodon:HisGTG
tRNA_number:trna1
Chromosome:15
Strand:+
Coordinate:Start Site(bp): 45493407        End Site(bp): 45493420+3

[7] gtRNAdb_ID:tRNA-His-GTG-1-8
Anticodon:HisGTG
tRNA_number:trna8
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 45492611-3        End Site(bp): 45492624

[8] gtRNAdb_ID:tRNA-His-GTG-1-7
Anticodon:HisGTG
tRNA_number:trna9
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 45490804-3        End Site(bp): 45490817

[9] gtRNAdb_ID:tRNA-His-GTG-1-5
Anticodon:HisGTG
tRNA_number:trna33
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27125964        End Site(bp): 27125977+3

[10] gtRNAdb_ID:tRNA-His-GTG-1-6
Anticodon:HisGTG
tRNA_number:trna7
Chromosome:9
Strand:-
Coordinate:Start Site(bp): 14433938-3        End Site(bp): 14433951



tsRNA Association Statistics

Total Associated Disease Number:7
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A