Entry Detail



General Information

Database ID:TRD02079
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Gln-CTG-005
tsRNA Type:tRF-3
Amino acid and Anticodon:GlnCTG
Sequence:TCTCGGTGGAACCTCCA
Related Target:N/A
Predicted Target:ST3GAL4//TOR3A//FNDC11//FNBP1//DCAKD//ORC1//CRTAP//SYNE2//FHAD1//TP53BP2
External Links:
MINTbase ID:tRF-17-WS72092
tRFdb ID:tRFdb-3004a

[1] gtRNAdb_ID:tRNA-Gln-CTG-5-1
Anticodon:GlnCTG
tRNA_number:trna42
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27263270        End Site(bp): 27263283+3

[2] gtRNAdb_ID:tRNA-Gln-CTG-4-1
Anticodon:GlnCTG
tRNA_number:trna112
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 147737382-3        End Site(bp): 147737395

[3] gtRNAdb_ID:tRNA-Gln-CTG-4-2
Anticodon:GlnCTG
tRNA_number:trna28
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 149186183        End Site(bp): 149186196+3

[4] gtRNAdb_ID:tRNA-Gln-CTG-3-1
Anticodon:GlnCTG
tRNA_number:trna15
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 145963362        End Site(bp): 145963375+3

[5] gtRNAdb_ID:tRNA-Gln-CTG-3-2
Anticodon:GlnCTG
tRNA_number:trna19
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 147505096        End Site(bp): 147505109+3

[6] gtRNAdb_ID:tRNA-Gln-CTG-2-1
Anticodon:GlnCTG
tRNA_number:trna146
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27515531-3        End Site(bp): 27515544

[7] gtRNAdb_ID:tRNA-Gln-CTG-1-4
Anticodon:GlnCTG
tRNA_number:trna7
Chromosome:15
Strand:-
Coordinate:Start Site(bp): 66161400-3        End Site(bp): 66161413

[8] gtRNAdb_ID:tRNA-Gln-CTG-1-5
Anticodon:GlnCTG
tRNA_number:trna3
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8023128        End Site(bp): 8023141+3

[9] gtRNAdb_ID:tRNA-Gln-CTG-1-1
Anticodon:GlnCTG
tRNA_number:trna1
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 18836460        End Site(bp): 18836473+3

[10] gtRNAdb_ID:tRNA-Gln-CTG-1-2
Anticodon:GlnCTG
tRNA_number:trna49
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27487366        End Site(bp): 27487379+3

[11] gtRNAdb_ID:tRNA-Gln-CTG-1-3
Anticodon:GlnCTG
tRNA_number:trna99
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28909378-3        End Site(bp): 28909391



tsRNA Association Statistics

Total Associated Disease Number:21
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D010051DOID:2394
Disease Name:Ovarian Neoplasmsovarian cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Urogenital Diseases//Endocrine System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. A female reproductive organ cancer that is located_in the ovary.
Alias:Cancer of Ovary//Cancer of the Ovary//Neoplasms, Ovarian//Ovarian Cancer//Ovary Cancer//Ovary Neoplasmsmalignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the Ovary



Disease Association Statistics

Total Associated tsRNA Number:74
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:33860037
Disease Name:Ovarian Neoplasms
Tissue:Ovarian
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:There are a total of 20 significantly upregulated and 15 significantly downregulated tRFs and tiRNAs between the cancer group and the paracarcinoma group.
Comparision:Cancer VS Normal
Mechanism:The upregulated tRFs and tiRNAs are mucin-type O-glycan biosynthesis, glycosphingolipid biosynthesis, the glucagon signaling pathway, the AMPK signaling pathway, maturity-onset diabetes of the young, glycosphingolipid biosynthesis, the insulin signaling pathway, insulin resistance, leukocyte transendothelial migration, starch, and sucrose metabolism.