Entry Detail


General Information

Database ID:TRD01955
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-006936
tsRNA Type:tRF-3
Amino acid and Anticodon:ArgACG
Sequence:TCCTGGCTGGCTCGCC
Related Target:N/A
Predicted Target:CCDC157//SYNE1//VPS53//PHF12//FURIN//PPT2-EGFL8//CERS6//PANK4//GATAD2B//CARD10
External Links:
MINTbase ID:tRF-16-8YQ84VD
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Arg-ACG-2-1
Anticodon:ArgACG
tRNA_number:trna11
Chromosome:3
Strand:-
Coordinate:Start Site(bp): 45730491-2        End Site(bp): 45730504

[2] gtRNAdb_ID:tRNA-Arg-ACG-2-4
Anticodon:ArgACG
tRNA_number:trna138
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27638344-2        End Site(bp): 27638357

[3] gtRNAdb_ID:tRNA-Arg-ACG-2-2
Anticodon:ArgACG
tRNA_number:trna156
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27181623-2        End Site(bp): 27181636

[4] gtRNAdb_ID:tRNA-Arg-ACG-2-3
Anticodon:ArgACG
tRNA_number:trna36
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 27183011        End Site(bp): 27183024+2

[5] gtRNAdb_ID:tRNA-Arg-ACG-1-3
Anticodon:ArgACG
tRNA_number:trna7
Chromosome:14
Strand:+
Coordinate:Start Site(bp): 23398969        End Site(bp): 23398982+2

[6] gtRNAdb_ID:tRNA-Arg-ACG-1-1
Anticodon:ArgACG
tRNA_number:trna6
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26328427        End Site(bp): 26328440+2

[7] gtRNAdb_ID:tRNA-Arg-ACG-1-2
Anticodon:ArgACG
tRNA_number:trna8
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26537785        End Site(bp): 26537798+2



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Down-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A