Entry Detail



General Information

Database ID:TRD01916
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-18-8R6546D2
tsRNA Type:tRF-3
Amino acid and Anticodon:AlaAGC;AlaTGC
Sequence:TCCCCGGCACCTCCACCA
Related Target:N/A
Predicted Target:SEC14L1//RAB43//ISY1-RAB43//FAM171A2//SMTN//RIC3//RETREG3//EGLN3//DCHS1//PLXNB1
External Links:
MINTbase ID:tRF-18-8R6546D2
tRFdb ID:tRNA-Ala-AGC-3-1

[1] gtRNAdb_ID:tRNA-Ala-AGC-3-1
Anticodon:AlaAGC
tRNA_number:trna65
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28574990        End Site(bp): 28575004+3

[2] gtRNAdb_ID:tRNA-Ala-AGC-2-2
Anticodon:AlaAGC
tRNA_number:trna101
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28831462-3        End Site(bp): 28831476

[3] gtRNAdb_ID:tRNA-Ala-AGC-2-1
Anticodon:AlaAGC
tRNA_number:trna102
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28806221-3        End Site(bp): 28806235

[4] gtRNAdb_ID:tRNA-Ala-TGC-6-1
Anticodon:AlaTGC
tRNA_number:trna113
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28726141-3        End Site(bp): 28726155

[5] gtRNAdb_ID:tRNA-Ala-TGC-1-1
Anticodon:AlaTGC
tRNA_number:trna110
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 28757547-3        End Site(bp): 28757561



tsRNA Association Statistics

Total Associated Disease Number:3
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D020521N/A
Disease Name:StrokeN/A
Category:MeSHDisease Ontology
Type:Nervous System Diseases//Cardiovascular DiseasesN/A
Define:A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)N/A
Alias:Apoplexy//CVA (Cerebrovascular Accident)//Cerebral Stroke//Cerebrovascular Accident//Cerebrovascular Accident, Acute//Cerebrovascular Apoplexy//Cerebrovascular Stroke//Stroke, Acute//Vascular Accident, BrainN/A



Disease Association Statistics

Total Associated tsRNA Number:46
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:33288717
Disease Name:Stroke
Tissue:N/A
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//High-throughput sequencing
Description:Furthermore,lipopolysaccharide stimulation of murine RAW 264.7 cells and human CD14+ monocytes Up-Regulation the top six stroke-perturbed tRFs,and overexpression of stroke-inducible tRF-22-WE8SPOX52 using a single-stranded RNA mimic induced down-regulation of immune regulator Z-DNA binding protein 1.
Comparision:N/A
Mechanism:N/A