tsRNADisease

Entry Detail

General Information

Database ID:	TRD01843
Confidence:	High
Contents:	>> tsRNA Information >> tsRNA Association Statistics >> Disease Information >> Disease Association Statistics >> Evidence Support >> Reference

tsRNA Information

tsRNA Name:

tRF-03357

tsRNA Type:

tRF-1

Amino acid and Anticodon:

N/A

Sequence:

N/A

Related Target:

Predicted Target:

External Links:

MINTbase ID:	N/A
tRFdb ID:	N/A

tsRNA Association Statistics

Total Associated Disease Number:	3 More Information
Network: (Display the first 15 nodes)

Disease Information

	MeSH	Disease Ontology
Disease ID:	D010051	DOID:2394
Disease Name:	Ovarian Neoplasms	ovarian cancer
Category:	MeSH	Disease Ontology
Type:	Neoplasms//Urogenital Diseases//Endocrine System Diseases	disease of anatomical entity//disease of cellular proliferation
Define:	Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	A female reproductive organ cancer that is located_in the ovary.
Alias:	Cancer of Ovary//Cancer of the Ovary//Neoplasms, Ovarian//Ovarian Cancer//Ovary Cancer//Ovary Neoplasms	malignant Ovarian tumor//malignant tumour of ovary//ovarian neoplasm//ovary neoplasm//primary ovarian cancer//tumor of the Ovary

Disease Association Statistics

Total Associated tsRNA Number:	74 More Information
Network: (Display the first 15 nodes)

Evidence Support

Strong Evidence:	RT-PCR
Weak Evidence:	High-throughput sequencing//High-throughput sequencing

Reference

[1] PubMed ID:	31496739
Disease Name:	Ovarian Neoplasms
Tissue:	Serum
Dysfunction Pattern:	Up-Regulation
Validated Method:	RT-PCR//High-throughput sequencing//High-throughput sequencing
Description:	tRF-03357 significantly promotes the proliferation, migration and invasion of ovarian cancer cells. This study might provide a potential diagnostic and therapeutic target for ovarian cancer.
Comparision:	Cancer VS Normal
Mechanism:	In this study, we found that tRF-03357 downregulated its predictive target gene HMBOX1, suggesting that tRF03357 might function similarly to a miRNA in ovarian cancer.