Entry Detail


General Information

Database ID:TRD01761
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-Ser-TGA-005
tsRNA Type:tRF-1
Amino acid and Anticodon:SerTGA
Sequence:GAAGCGGGTGCTCTTAT
Related Target:N/A
Predicted Target:GOLGA7B//CDK2AP2//ARHGAP20//ASS1//UBE2L3//UBE2L5//COG5//SYT8//NDUFB4//GINS3
External Links:
MINTbase ID:N/A
tRFdb ID:N/A



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D000077192DOID:3910
Disease Name:Adenocarcinoma of Lunglung adenocarcinoma
Category:MeSHDisease Ontology
Type:Neoplasmsdisease of anatomical entity//disease of cellular proliferation
Define:A carcinoma originating in the lung and the most common lung cancer type in never-smokers. Malignant cells exhibit distinct features such as glandular epithelial, or tubular morphology. Mutations in KRAS, EGFR, BRAF, and ERBB2 genes are associated with this cancer.A lung non-small cell carcinoma that derives_from epithelial cells of glandular origin.
Alias:Lung Adenocarcinomaadenocarcinoma of lung//bronchogenic lung adenocarcinoma//nonsmall cell adenocarcinoma



Disease Association Statistics

Total Associated tsRNA Number:203
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:Data Mining



Reference

[1] PubMed ID:33986867
Disease Name:Adenocarcinoma of Lung
Tissue:N/A
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR//Data Mining
Description:Reverse transcription-quantitative PCR verification revealed that the expression levels of tiRNA-Lys-CTT-002,tRF-Val-CAC-010 and tRF-Val-CAC-011 were significantly upregulated,while those of tRF-Ser-TGA-005 were downregulated in lung adenocarcinoma tissues.
Comparision:N/A
Mechanism:N/A