Entry Detail


General Information

Database ID:TRD01732
Confidence:Low
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-1020
tsRNA Type:tRF-1
Amino acid and Anticodon:PheGAA
Sequence:GAGAGCGCTCGGTTTTT
Related Target:DVL2
Predicted Target:PLK2//NCAM1//JCAD//SLC22A23//PARS2//KLHL36//DPPA4//CD99//PAPPA//CXorf40B
External Links:
MINTbase ID:N/A
tRFdb ID:tRFdb-1020



tsRNA Association Statistics

Total Associated Disease Number:7
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D003925DOID:11713
Disease Name:Diabetic Angiopathiesdiabetic angiopathy
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Endocrine System Diseasesdisease of anatomical entity
Define:VASCULAR DISEASES that are associated with DIABETES MELLITUS. A peripheral vascular disease that is characterized by narrowing of the arteries as a complication arising from chronic diabetes.
Alias:Diabetic Vascular Complications//Diabetic Vascular Diseases//Microangiopathy, Diabeticdiabetic peripheral angiopathy//Diabetic vascular disorder



Disease Association Statistics

Total Associated tsRNA Number:28
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:N/A



Reference

[1] PubMed ID:36128646
Disease Name:Diabetic Angiopathies
Tissue:N/A
Dysfunction Pattern:Down-Regulation
Validated Method:RT-PCR
Description:tRNA-derived fragment tRF-1020 ameliorates diabetes-induced retinal microvascular complications.
Comparision:Diabetic Retinal Vessels VS Retinal Endothelial Cells
Mechanism:tRF-1020 regulates endothelial angiogenic function by targeting DVL-2.