Entry Detail


General Information

Database ID:TRD01612
Confidence:High
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-17-18VBY9M
tsRNA Type:i-tRF
Amino acid and Anticodon:N/A
Sequence:AGTGGTAGAATTCTCGC
Related Target:N/A
Predicted Target:FCGR2A//HSPB2//HSPB2-C11orf52//ATE1//SIRT5//ARHGAP23//NCALD//SRGAP1//FAT3//C6orf47
External Links:
MINTbase ID:tRF-17-18VBY9M
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Gly-CCC-6-1
Anticodon:GlyCCC
tRNA_number:trna91
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149680251        End Site(bp): 149680267

[2] gtRNAdb_ID:tRNA-Glu-TTC-9-1
Anticodon:GluTTC
tRNA_number:trna17
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 204229172        End Site(bp): 204229188

[3] gtRNAdb_ID:tRNA-Gly-CCC-5-1
Anticodon:GlyCCC
tRNA_number:trna2
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17053793        End Site(bp): 17053809

[4] gtRNAdb_ID:tRNA-Gly-CCC-4-1
Anticodon:GlyCCC
tRNA_number:trna131
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 17004807        End Site(bp): 17004823

[5] gtRNAdb_ID:tRNA-Gly-CCC-1-1
Anticodon:GlyCCC
tRNA_number:trna133
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 16872475        End Site(bp): 16872491

[6] gtRNAdb_ID:tRNA-Gly-CCC-1-2
Anticodon:GlyCCC
tRNA_number:trna4
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 17188429        End Site(bp): 17188445

[7] gtRNAdb_ID:tRNA-Gly-GCC-5-1
Anticodon:GlyGCC
tRNA_number:trna18
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70822610        End Site(bp): 70822626

[8] gtRNAdb_ID:tRNA-Gly-GCC-3-1
Anticodon:GlyGCC
tRNA_number:trna25
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812155        End Site(bp): 70812171

[9] gtRNAdb_ID:tRNA-Gly-GCC-2-1
Anticodon:GlyGCC
tRNA_number:trna68
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 161493678        End Site(bp): 161493694

[10] gtRNAdb_ID:tRNA-Gly-GCC-2-5
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 70823423        End Site(bp): 70823439

[11] gtRNAdb_ID:tRNA-Gly-GCC-2-4
Anticodon:GlyGCC
tRNA_number:trna24
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 70812983        End Site(bp): 70812999

[12] gtRNAdb_ID:tRNA-Gly-GCC-2-6
Anticodon:GlyGCC
tRNA_number:trna5
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8029077        End Site(bp): 8029093

[13] gtRNAdb_ID:tRNA-Gly-GCC-2-2
Anticodon:GlyGCC
tRNA_number:trna19
Chromosome:2
Strand:-
Coordinate:Start Site(bp): 157257700        End Site(bp): 157257716

[14] gtRNAdb_ID:tRNA-Gly-GCC-2-3
Anticodon:GlyGCC
tRNA_number:trna128
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27870727        End Site(bp): 27870743

[15] gtRNAdb_ID:tRNA-Gly-GCC-1-1
Anticodon:GlyGCC
tRNA_number:trna35
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161413107        End Site(bp): 161413123

[16] gtRNAdb_ID:tRNA-Gly-GCC-1-2
Anticodon:GlyGCC
tRNA_number:trna37
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161420480        End Site(bp): 161420496

[17] gtRNAdb_ID:tRNA-Gly-GCC-1-3
Anticodon:GlyGCC
tRNA_number:trna39
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161427911        End Site(bp): 161427927

[18] gtRNAdb_ID:tRNA-Gly-GCC-1-4
Anticodon:GlyGCC
tRNA_number:trna41
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 161435271        End Site(bp): 161435287

[19] gtRNAdb_ID:tRNA-Gly-GCC-1-5
Anticodon:GlyGCC
tRNA_number:trna2
Chromosome:21
Strand:-
Coordinate:Start Site(bp): 18827148        End Site(bp): 18827164

[20] gtRNAdb_ID:tRNA-Val-CAC-8-1
Anticodon:ValCAC
tRNA_number:trna99
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 149294707        End Site(bp): 149294723



tsRNA Association Statistics

Total Associated Disease Number:1
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D013274 DOID:10534
Disease Name:Stomach Neoplasmsstomach cancer
Category:MeSHDisease Ontology
Type:Neoplasms//Digestive System Diseasesdisease of anatomical entity//disease of cellular proliferation
Define:Tumors or cancer of the STOMACH.A gastrointestinal system cancer that is located_in the stomach.
Alias:Cancer of Stomach//Cancer of the Stomach//Gastric Cancer//Gastric Cancer, Familial Diffuse//Gastric Neoplasms//Neoplasms, Gastric//Neoplasms, Stomach//Stomach Cancergastric cancer//gastric neoplasm



Disease Association Statistics

Total Associated tsRNA Number:79
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:RT-PCR
Weak Evidence:Sequencing



Reference

[1] PubMed ID:38767702
Disease Name:Stomach Neoplasms
Tissue:serum
Dysfunction Pattern:Up-Regulation
Validated Method:RT-PCR//Sequencing
Description:In this research, we screened a differentially expressed molecule tsRNA-Gly-i-0003 from the tsRFun database, called it tRF-17-18VBY9M according to MINT base v2.0, And verified that its expression level was consistent in gastric cancer tissues and serum, which were both significantly up-regulated, and thus hypothesized whether serum tRF-17- 18VBY9M could function as a new biomarker for GC diagnosis and monitoring.
Comparision:Cancer VS Normal
Mechanism:The Chi-square test demonstrated that high-expressed tRF-17-18VBY9M was closely associated with the T stage, tumor node metastasis stage (TNM), lymph node metastasis, and neurological/vascular invasion. ROC curve analysis revealed that the diagnostic value of tRF-17-18VBY9M in GC was superior to carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), and carbohydrate antigen 724 (CA724).