Entry Detail


General Information

Database ID:TRD01391
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:tRF-19-8FFDXXE5
tsRNA Type:i-tRF
Amino acid and Anticodon:SerGCT
Sequence:TCACAAGAACTGCTAACTC
Related Target:N/A
Predicted Target:MSH2//ZNF618//CNOT6L//MPDZ//ZNF248//SORT1//XKR4//RAB21//MAML3//ZNF540
External Links:
MINTbase ID:tRF-19-8FFDXXE5
tRFdb ID:N/A

[1] gtRNAdb_ID:-
Anticodon:SerGCT
tRNA_number:trnaMT
Chromosome:MT
Strand:+
Coordinate:Start Site(bp): 12215        End Site(bp): 12233



tsRNA Association Statistics

Total Associated Disease Number:5
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D006332N/A
Disease Name:CardiomegalyN/A
Category:MeSHDisease Ontology
Type:Cardiovascular Diseases//Pathological Conditions, Signs and SymptomsN/A
Define:Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.N/A
Alias:Cardiac Hypertrophy//Enlarged Heart//Heart Enlargement//Heart HypertrophyN/A



Disease Association Statistics

Total Associated tsRNA Number:68
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:37370960
Disease Name:Cardiomegaly
Tissue:Plasma
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:There were four upregulated tsRNAs, including tRF-19-8FFDXXE5, tRF-19-SWRYVMH0, tRF-16-Q622EVE, and tRF-26-YONONU3INDD, and five downregulated tsRNAs, including tRF-21-NB8PLML3E, tRF-18-F9LKXN05, tRF-21-SWRYVMMV0, tRF-16-R29P4PE, and tRF-30-3JVIJMRPFQ5D.
Comparision:Disease VS Control
Mechanism:N/A