Entry Detail


General Information

Database ID:TRD01242
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-004206
tsRNA Type:i-tRF
Amino acid and Anticodon:LysTTT
Sequence:AGTCGGTAGAGCATCAGA
Related Target:N/A
Predicted Target:WASF3//SH2D5//TM6SF1//OR8J1//SLC39A3//ITGAL//ARL4C//TNPO2//ANXA4//SLA
External Links:
MINTbase ID:tRF-18-1SS2PMX
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Lys-TTT-6-1
Anticodon:LysTTT
tRNA_number:trna149
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27302811        End Site(bp): 27302828

[2] gtRNAdb_ID:tRNA-Lys-TTT-5-1
Anticodon:LysTTT
tRNA_number:trna5
Chromosome:11
Strand:+
Coordinate:Start Site(bp): 59323915        End Site(bp): 59323932

[3] gtRNAdb_ID:tRNA-Lys-TTT-4-1
Anticodon:LysTTT
tRNA_number:trna143
Chromosome:6
Strand:-
Coordinate:Start Site(bp): 27559635        End Site(bp): 27559652

[4] gtRNAdb_ID:tRNA-Lys-TTT-3-1
Anticodon:LysTTT
tRNA_number:trna54
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 204475668        End Site(bp): 204475685

[5] gtRNAdb_ID:tRNA-Lys-TTT-3-2
Anticodon:LysTTT
tRNA_number:trna62
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 204476200        End Site(bp): 204476217

[6] gtRNAdb_ID:tRNA-Lys-TTT-3-4
Anticodon:LysTTT
tRNA_number:trna14
Chromosome:11
Strand:-
Coordinate:Start Site(bp): 59327850        End Site(bp): 59327867

[7] gtRNAdb_ID:tRNA-Lys-TTT-3-5
Anticodon:LysTTT
tRNA_number:trna2
Chromosome:17
Strand:+
Coordinate:Start Site(bp): 8022486        End Site(bp): 8022503

[8] gtRNAdb_ID:tRNA-Lys-TTT-3-3
Anticodon:LysTTT
tRNA_number:trna76
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 28918819        End Site(bp): 28918836



tsRNA Association Statistics

Total Associated Disease Number:2
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A