Entry Detail


General Information

Database ID:TRD01181
Confidence:Median
Contents:>> tsRNA Information
>> tsRNA Association Statistics
>> Disease Information
>> Disease Association Statistics
>> Evidence Support
>> Reference



tsRNA Information

tsRNA Name:AS-tDR-007329
tsRNA Type:i-tRF
Amino acid and Anticodon:LysCTT
Sequence:ACTCTTAATCTCAGGGTCGTG
Related Target:N/A
Predicted Target:CEP41//LSAMP//DIDO1//GJD3//SERAC1//SORCS1//BTBD10//ARMCX4//RUBCN//ZNF830
External Links:
MINTbase ID:tRF-21-E7UM8KSW0
tRFdb ID:N/A

[1] gtRNAdb_ID:tRNA-Lys-CTT-14-1
Anticodon:LysCTT
tRNA_number:trna13
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3246183        End Site(bp): 3246203

[2] gtRNAdb_ID:tRNA-Lys-CTT-12-1
Anticodon:LysCTT
tRNA_number:trna8
Chromosome:1
Strand:+
Coordinate:Start Site(bp): 39970225        End Site(bp): 39970245

[3] gtRNAdb_ID:tRNA-Lys-CTT-8-1
Anticodon:LysCTT
tRNA_number:trna5
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3214969        End Site(bp): 3214989

[4] gtRNAdb_ID:tRNA-Lys-CTT-5-1
Anticodon:LysCTT
tRNA_number:trna30
Chromosome:16
Strand:-
Coordinate:Start Site(bp): 3230577        End Site(bp): 3230597

[5] gtRNAdb_ID:tRNA-Lys-CTT-4-1
Anticodon:LysCTT
tRNA_number:trna10
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3241531        End Site(bp): 3241551

[6] gtRNAdb_ID:tRNA-Lys-CTT-2-1
Anticodon:LysCTT
tRNA_number:trna119
Chromosome:1
Strand:-
Coordinate:Start Site(bp): 145395544        End Site(bp): 145395564

[7] gtRNAdb_ID:tRNA-Lys-CTT-2-5
Anticodon:LysCTT
tRNA_number:trna7
Chromosome:16
Strand:+
Coordinate:Start Site(bp): 3225722        End Site(bp): 3225742

[8] gtRNAdb_ID:tRNA-Lys-CTT-2-3
Anticodon:LysCTT
tRNA_number:trna11
Chromosome:5
Strand:-
Coordinate:Start Site(bp): 180649001        End Site(bp): 180649021

[9] gtRNAdb_ID:tRNA-Lys-CTT-2-2
Anticodon:LysCTT
tRNA_number:trna9
Chromosome:5
Strand:+
Coordinate:Start Site(bp): 180634785        End Site(bp): 180634805

[10] gtRNAdb_ID:tRNA-Lys-CTT-2-4
Anticodon:LysCTT
tRNA_number:trna13
Chromosome:6
Strand:+
Coordinate:Start Site(bp): 26556804        End Site(bp): 26556824



tsRNA Association Statistics

Total Associated Disease Number:7
More Information
Network:
(Display the first 15 nodes)



Disease Information

 MeSHDisease Ontology
Disease ID:D051436DOID:784
Disease Name:Renal Insufficiency, Chronicchronic kidney disease
Category:MeSHDisease Ontology
Type:Urogenital Diseases//Pathological Conditions, Signs and Symptomsdisease of anatomical entity
Define:Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)A kidney failure that is characterized by the gradual loss of kidney function.
Alias:Chronic Kidney Diseases//Chronic Kidney Insufficiency//Chronic Renal Diseases//Chronic Renal Insufficiency//Kidney Insufficiency, ChronicN/A



Disease Association Statistics

Total Associated tsRNA Number:197
More Information
Network:
(Display the first 15 nodes)



Evidence Support

Strong Evidence:N/A
Weak Evidence:High-throughput sequencing



Reference

[1] PubMed ID:31629473
Disease Name:Renal Insufficiency, Chronic
Tissue:Kidney
Dysfunction Pattern:Up-Regulation
Validated Method:High-throughput sequencing
Description:In this study, 147 differentially expressed (fold change > 2, P < 0.05) tRFs were identified. Specifically, 69 tRFs were up-regulated and 70 tRFs were down-regulated.
Comparision:Differentiated Podocytes VS Undifferentiated Podocytes
Mechanism:N/A